About: Susceptibility of reservoir small mammalian species to the infection by F. tularensis     Goto   Sponge   NotDistinct   Permalink

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  • Tularaemia is a re-emerging zoonosis of natural nidality maintained by small mammalian species, in particular. By means of experimental infection we compared the susceptibility of the house mouse (Mus musculus), common vole (Microtus arvalis) and yellow-necked fieldmouse (Apodemus flavicollis) to the infection by Francisella tularensis. Experimental animals were inoculated by intraperitoneal injection of 310 bacterial cells and studied regarding the survival time and differential leukocyte count. The mean survival in the house mouse, common vole and yellow-necked fieldmouse was 4.25, 6 and 4 days, respectively. Bacteremia was present in blood smears of all common voles and one yellow-necked fieldmouse prior to death. The differential leukocyte count could be characterised by neutrophilia initially, subsequent neutropenia and lymphocytosis. The results demonstrate that the yellow-necked fieldmouse is even more susceptible to the infection by F. tularensis than the house mouse and that the common vole
  • Tularaemia is a re-emerging zoonosis of natural nidality maintained by small mammalian species, in particular. By means of experimental infection we compared the susceptibility of the house mouse (Mus musculus), common vole (Microtus arvalis) and yellow-necked fieldmouse (Apodemus flavicollis) to the infection by Francisella tularensis. Experimental animals were inoculated by intraperitoneal injection of 310 bacterial cells and studied regarding the survival time and differential leukocyte count. The mean survival in the house mouse, common vole and yellow-necked fieldmouse was 4.25, 6 and 4 days, respectively. Bacteremia was present in blood smears of all common voles and one yellow-necked fieldmouse prior to death. The differential leukocyte count could be characterised by neutrophilia initially, subsequent neutropenia and lymphocytosis. The results demonstrate that the yellow-necked fieldmouse is even more susceptible to the infection by F. tularensis than the house mouse and that the common vole (en)
  • Tularémie v Evropě nově nabývá na významu jako zoonóza s přírodní ohniskovostí. Na udržování přírodních ohnisek se podílejí drobní savci (myš domácí, hraboš polní a myšice lesní), jejichž vnímavost k infekci Francisella tularensis byla předmětem této studie. Experimentální zvířata byla inokulována 310 bakteriálními buňkami a sledována byla doba přežívání a vývoj hematologických a biochemických parametrů. Průměrná doba přežívání myši domácí byla 4,25 dní, hraboše polního 6 dní a myšice lesní 4 dny. Diferenciální rozpočet byl zpočátku charakterizován neutrofilní, poté neutropenií a dále lymfocytózou. Výsledky prokazují, že myšice je ještě více citlivá k infekci Francisella tularensis než myš domácí. Naproti tomu hraboš polní může být významným rezervoárovým druhem pro tularémii. (cs)
Title
  • Susceptibility of reservoir small mammalian species to the infection by F. tularensis
  • Vnímavost rezervoárových drobných savců k infekci F. tularensis (cs)
  • Susceptibility of reservoir small mammalian species to the infection by F. tularensis (en)
skos:prefLabel
  • Susceptibility of reservoir small mammalian species to the infection by F. tularensis
  • Vnímavost rezervoárových drobných savců k infekci F. tularensis (cs)
  • Susceptibility of reservoir small mammalian species to the infection by F. tularensis (en)
skos:notation
  • RIV/62157124:16270/06:00000986!RIV07-MSM-16270___
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  • 502595
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  • RIV/62157124:16270/06:00000986
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  • European brown hare; common vole; yellow-necked fieldmouse; house mouse; tularemia (en)
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  • [6FA7295984AC]
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  • Banďouchová, Hana
  • Beklová, Miroslava
  • Horáková, Jana
  • Pikula, Jiří
  • Treml, František
  • Skočovská, Blanka
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  • 16270
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