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| Description
| - and Pharmaceutical Sciences Brno, Czech Republic, katka.machacek@gmail.com Objective: As the consequences of majority of colic episodes in horses, the severe tissue damage or endotoxaemia is present. Both of them can lead to any kind of thrombo-hemorrhagic disorders. Even though clinical stage of these disorders does not generally occur in horses, fibrin deposits can be detected by the histological examination. Early diagnose could prevent any other complications and improve post-operative treatment of the horses. The aim of this study was to evaluate D-dimer measuring and thromboelastography as a diagnostic tool in detecting thrombo-hemorrhagic complications in colic horses. Design and method: Blood was collected from 31 horses with acute colic right after admission. Control samples were taken from 25 healthy horses. Activated partial thromboplastin time (aPTT), prothrombin time (PT) and fibrinogen concentration (FBG) were measured from citrated plasma and D-dimer level (DD) were measured from citrated plasma. R-time (R), K-time (K), alfa-angle (A) and maximal amplitude (MA) were measured from citrated blood within the scope of thromboelastography. Results: Significant differences were present between control samples and patients in following (median values shown) - PT (16.0 vs 17.3s, p=0.021), FBG (1.82 vs. 1.19g/l, p=0.005), DD (0.0 vs 0.2mg/l, p=0.0003), R (10.0 vs. 7.1 min, p=0.029). Between conservatively treated horses and horses that underwent surgery, significant difference was present in DD (0.1 vs. 0.3mg/l, p=0.014). Conclusion: Thrombo-hemorrhagical complications are present in horses with acute abdominal episode even though it is not clinically seen in horses. The most significant parameter of all was DD; most significant thromboelastography parameter was R-time.
- and Pharmaceutical Sciences Brno, Czech Republic, katka.machacek@gmail.com Objective: As the consequences of majority of colic episodes in horses, the severe tissue damage or endotoxaemia is present. Both of them can lead to any kind of thrombo-hemorrhagic disorders. Even though clinical stage of these disorders does not generally occur in horses, fibrin deposits can be detected by the histological examination. Early diagnose could prevent any other complications and improve post-operative treatment of the horses. The aim of this study was to evaluate D-dimer measuring and thromboelastography as a diagnostic tool in detecting thrombo-hemorrhagic complications in colic horses. Design and method: Blood was collected from 31 horses with acute colic right after admission. Control samples were taken from 25 healthy horses. Activated partial thromboplastin time (aPTT), prothrombin time (PT) and fibrinogen concentration (FBG) were measured from citrated plasma and D-dimer level (DD) were measured from citrated plasma. R-time (R), K-time (K), alfa-angle (A) and maximal amplitude (MA) were measured from citrated blood within the scope of thromboelastography. Results: Significant differences were present between control samples and patients in following (median values shown) - PT (16.0 vs 17.3s, p=0.021), FBG (1.82 vs. 1.19g/l, p=0.005), DD (0.0 vs 0.2mg/l, p=0.0003), R (10.0 vs. 7.1 min, p=0.029). Between conservatively treated horses and horses that underwent surgery, significant difference was present in DD (0.1 vs. 0.3mg/l, p=0.014). Conclusion: Thrombo-hemorrhagical complications are present in horses with acute abdominal episode even though it is not clinically seen in horses. The most significant parameter of all was DD; most significant thromboelastography parameter was R-time. (en)
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| Title
| - Caolin activated tromboelastography in horses: comparison between healthy animals and patients with acute gastrointestinal episode.
- Caolin activated tromboelastography in horses: comparison between healthy animals and patients with acute gastrointestinal episode. (en)
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| skos:prefLabel
| - Caolin activated tromboelastography in horses: comparison between healthy animals and patients with acute gastrointestinal episode.
- Caolin activated tromboelastography in horses: comparison between healthy animals and patients with acute gastrointestinal episode. (en)
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| skos:notation
| - RIV/62157124:16170/14:43873282!RIV15-MSM-16170___
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/62157124:16170/14:43873282
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...iv/tvurceVysledku
| - Uhríková, Ivana
- Macháčková, Kateřina
- Doubek, Jaroslav
- Bošelová, Martina
- Drábková, Zuzana
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| http://localhost/t...ganizacniJednotka
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