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| rdf:type
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| Description
| - Background: Disseminated intravascular coagulation (DIC) is a frequent complication of diseases such as gastric dilatation-volvulus syndrome (GDV) or hemangiosarcoma (H). Different pathogenesis of DIC in expected in these diseases with different alterations in hemostatic profiles. Objective: The aim of this study is to describe and compare alterations in hemostatic profiles in dogs with GDV or H. Methods: Blood was collected from dogs with GDV (n=12) and H (n=6) at admission into tubes containing citrate and EDTA. Platelet count (PLT), prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen (FBG) and D-dimers were measured and thromboelastography was performed in the samples. Results: Obtained results were: median (GDV vs. H) PLT 186 vs. 74*109/l (min-max, 89-325 vs. 50-111*109/l), aPTT 21.7 vs. 21.2 s (18.4-32.4 vs. 19.9-28.6 s), PT 10.7 vs. 11.1 s (9.7-14.8 vs. 8.7-12.4 s), FBG 1.2 vs. 2.24 g/l (0.2-2.0 vs. 1.8-4.9 g/l), D-dimers 0.4 vs. 0.6 (0.1-1.6 vs. 0.3-2.7), reaction time (R) 3.5 vs. 2.6 min (1.6-4.5 vs. 0.8-4.2 min), clot formation time (K) 2.0 vs. 2.2 min (1.4-6.9 vs. 0.8-15.9 min), angle alpha (A) 68.5 vs. 61.3 degrees (40.3-71.9 vs. 30.3-80.7 degrees) and maximal amplitude (MA) 49.1 vs. 53.4 mm (32.1-63.9 vs. 22.2-69.2 mm). Platelet count was significantly lower and fibrinogen concentration higher in dogs with H in comparison to GDV (p{0.05). The most frequent alterations were prolongation of aPTT (80%) and elevation of D-dimers (75%) in dogs with GDV; in dogs with H prolongation of aPTT (100%) and low PLT (90%). Conclusion: GDV and H are associated with various changes in hemostatic profiles. Further studies may reveal important factors in initiation of DIC during these diseases.
- Background: Disseminated intravascular coagulation (DIC) is a frequent complication of diseases such as gastric dilatation-volvulus syndrome (GDV) or hemangiosarcoma (H). Different pathogenesis of DIC in expected in these diseases with different alterations in hemostatic profiles. Objective: The aim of this study is to describe and compare alterations in hemostatic profiles in dogs with GDV or H. Methods: Blood was collected from dogs with GDV (n=12) and H (n=6) at admission into tubes containing citrate and EDTA. Platelet count (PLT), prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen (FBG) and D-dimers were measured and thromboelastography was performed in the samples. Results: Obtained results were: median (GDV vs. H) PLT 186 vs. 74*109/l (min-max, 89-325 vs. 50-111*109/l), aPTT 21.7 vs. 21.2 s (18.4-32.4 vs. 19.9-28.6 s), PT 10.7 vs. 11.1 s (9.7-14.8 vs. 8.7-12.4 s), FBG 1.2 vs. 2.24 g/l (0.2-2.0 vs. 1.8-4.9 g/l), D-dimers 0.4 vs. 0.6 (0.1-1.6 vs. 0.3-2.7), reaction time (R) 3.5 vs. 2.6 min (1.6-4.5 vs. 0.8-4.2 min), clot formation time (K) 2.0 vs. 2.2 min (1.4-6.9 vs. 0.8-15.9 min), angle alpha (A) 68.5 vs. 61.3 degrees (40.3-71.9 vs. 30.3-80.7 degrees) and maximal amplitude (MA) 49.1 vs. 53.4 mm (32.1-63.9 vs. 22.2-69.2 mm). Platelet count was significantly lower and fibrinogen concentration higher in dogs with H in comparison to GDV (p{0.05). The most frequent alterations were prolongation of aPTT (80%) and elevation of D-dimers (75%) in dogs with GDV; in dogs with H prolongation of aPTT (100%) and low PLT (90%). Conclusion: GDV and H are associated with various changes in hemostatic profiles. Further studies may reveal important factors in initiation of DIC during these diseases. (en)
|
| Title
| - Hemostatic profile in dogs with gastric dilatation-volvulus syndrome or hemangiosarcoma: preliminary results.
- Hemostatic profile in dogs with gastric dilatation-volvulus syndrome or hemangiosarcoma: preliminary results. (en)
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| skos:prefLabel
| - Hemostatic profile in dogs with gastric dilatation-volvulus syndrome or hemangiosarcoma: preliminary results.
- Hemostatic profile in dogs with gastric dilatation-volvulus syndrome or hemangiosarcoma: preliminary results. (en)
|
| skos:notation
| - RIV/62157124:16170/13:43872494!RIV14-MSM-16170___
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/62157124:16170/13:43872494
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - hemostasis; hemangiosarcoma; GDV (en)
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| http://linked.open.../riv/klicoveSlovo
| |
| http://linked.open...ontrolniKodProRIV
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| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
| |
| http://linked.open...iv/tvurceVysledku
| - Raušerová-Lexmaulová, Leona
- Uhríková, Ivana
- Doubek, Jaroslav
- Rybová, Marie
|
| http://localhost/t...ganizacniJednotka
| |
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