About: Influence of drugs on the response characteristics of the LiDCO sensor: An in vitro study

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About: Influence of drugs on the response characteristics of the LiDCO sensor: An in vitro study Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	BackgroundIn a previous study, the authors found a large bias (50%) for lithium (LiDCO) compared with thermodilution cardiac output measurement methods in ponies receiving i.v. infusions of xylazine, ketamine, and midazolam. This prompted the authors to examine the effect of drugs on the LiDCO sensor. A number of drugs influenced the accuracy of the LiDCO sensor in vitro but, based on published pharmacokinetic data, only xylazine, ketamine, lidocaine, and rocuronium may cause biases at clinically relevant concentrations. These findings need to be confirmed in vivo. Relevant (}3 mV) changes in sensor voltages due to the presence of drugs may indicate possible interactions with the LiDCO sensor. BackgroundIn a previous study, the authors found a large bias (50%) for lithium (LiDCO) compared with thermodilution cardiac output measurement methods in ponies receiving i.v. infusions of xylazine, ketamine, and midazolam. This prompted the authors to examine the effect of drugs on the LiDCO sensor. A number of drugs influenced the accuracy of the LiDCO sensor in vitro but, based on published pharmacokinetic data, only xylazine, ketamine, lidocaine, and rocuronium may cause biases at clinically relevant concentrations. These findings need to be confirmed in vivo. Relevant (}3 mV) changes in sensor voltages due to the presence of drugs may indicate possible interactions with the LiDCO sensor. (en)
Title	Influence of drugs on the response characteristics of the LiDCO sensor: An in vitro study Influence of drugs on the response characteristics of the LiDCO sensor: An in vitro study (en)
skos:prefLabel	Influence of drugs on the response characteristics of the LiDCO sensor: An in vitro study Influence of drugs on the response characteristics of the LiDCO sensor: An in vitro study (en)
skos:notation	RIV/62157124:16170/13:43871786!RIV14-MSM-16170___
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM6215712403)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Kabeš, Radovan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Veterinární a farmaceutická univerzita Brno / Fakulta veterinárního lékařství
http://linked.open...dnocenehoVysledku	79741
http://linked.open...ai/riv/idVysledku	RIV/62157124:16170/13:43871786
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	veterinary drugs; physiological monitoring; lithium; i.v. anaesthesia; cardiac output (en)
http://linked.open.../riv/klicoveSlovo	veterinary drugs lithium i.v. anaesthesia physiological monitoring cardiac output
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[655793560ED5]
http://linked.open...i/riv/nazevZdroje	British journal of anaesthesia
http://linked.open...in/vavai/riv/obor	GJ
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	110
http://linked.open...iv/tvurceVysledku	Kabeš, Radovan Ambrisko, Tamas Moens, Yves
http://linked.open...ain/vavai/riv/wos	000313826500021
http://linked.open...n/vavai/riv/zamer	Active creation of health, yield and performance of the large animals
issn	0007-0912
number of pages	6 (xsd:int)
http://bibframe.org/vocab/doi	10.1093/bja/aes380
http://localhost/t...ganizacniJednotka	16170

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