About: Localization of c-MYB in differentiated cells during postnatal molar and alveolar bone development

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About: Localization of c-MYB in differentiated cells during postnatal molar and alveolar bone development Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The MYB family of transcription activators has been associated with a high proliferation rate and an undifferentiated state of cells in a number of tissues. Recently emerging data suggest that these molecules may also play a role in differentiation. In this study, the pattern of expression of c-MYB was followed during postnatal stages of mouse molar odontogenesis using immunohistochemistry on serial sections. Along with an abundance of the c-MYB protein in proliferating zones, we confirmed the presence of this protein in differentiated ameloblasts, odontoblasts, and osteoblasts. In addition, c-MYB was also found in cementoblasts and alveolar fibroblasts. These findings suggest integration of c-MYB into regulatory networks during hard-tissue differentiation and mineralization. The MYB family of transcription activators has been associated with a high proliferation rate and an undifferentiated state of cells in a number of tissues. Recently emerging data suggest that these molecules may also play a role in differentiation. In this study, the pattern of expression of c-MYB was followed during postnatal stages of mouse molar odontogenesis using immunohistochemistry on serial sections. Along with an abundance of the c-MYB protein in proliferating zones, we confirmed the presence of this protein in differentiated ameloblasts, odontoblasts, and osteoblasts. In addition, c-MYB was also found in cementoblasts and alveolar fibroblasts. These findings suggest integration of c-MYB into regulatory networks during hard-tissue differentiation and mineralization. (en)
Title	Localization of c-MYB in differentiated cells during postnatal molar and alveolar bone development Localization of c-MYB in differentiated cells during postnatal molar and alveolar bone development (en)
skos:prefLabel	Localization of c-MYB in differentiated cells during postnatal molar and alveolar bone development Localization of c-MYB in differentiated cells during postnatal molar and alveolar bone development (en)
skos:notation	RIV/62157124:16170/12:43871268!RIV13-MSM-16170___
http://linked.open...avai/riv/aktivita	I P V Z
http://linked.open...avai/riv/aktivity	I, P(GA301/09/1115), P(GCP302/12/J059), V, Z(AV0Z50450515)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Buchtová, Marcela Matalová, Eva Lungová, Vlasta
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Veterinární a farmaceutická univerzita Brno / Fakulta veterinárního lékařství
http://linked.open...dnocenehoVysledku	147323
http://linked.open...ai/riv/idVysledku	RIV/62157124:16170/12:43871268
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	cytodifferentiation; bone; postnatal; tooth; c-myb (en)
http://linked.open.../riv/klicoveSlovo	bone tooth c-myb cytodifferentiation postnatal
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[FE7FFF1B7646]
http://linked.open...i/riv/nazevZdroje	European Journal of Oral Sciences
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	The role of c-Myb and Cox-2 proteins in colon carcinogenesis Cellular and molecular mechanisms in tooth-bone complex formation
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	120
http://linked.open...iv/tvurceVysledku	Buchtová, Marcela Knopfová, Lucia Šmarda, Jan Janečková, Eva Matalová, Eva Lungová, Vlasta Tucker, Abigail S
http://linked.open...ain/vavai/riv/wos	000311379100003
http://linked.open...n/vavai/riv/zamer	Genetic, functional and developmental potential of animal cells, tissues and organisms: their use in medicine, ecology and agriculture
issn	0909-8836
number of pages	10 (xsd:int)
http://bibframe.org/vocab/doi	10.1111/j.1600-0722.2012.01004.x
http://localhost/t...ganizacniJednotka	16170

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