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  • Polysaccharide storage myopathy je onemocnění projevující se opakovanými epizodami akutní rhabdomyolýzy většinou souvisejícími se zátěží koně. Onemocnění není léčitelné, ale úpravou diety a managementu koně lze snížit výskyt epizod na minimum nebo jim i zcela předejít. V článku je popsána anamnéza, klinické a laboratorní vyšetření, terapie a management případu PSSM u pětileté klisny plemene Quarter horse. (cs)
  • Five years old Quarter Horse mare was presented with a history of repeated attacks of stiffness and dark urine. Onset of clinical signs (back and rear legs stiffness, trembling and sweating) was observed within first 30 minutes of exercise and disappeared within four hours. All attacks were observed during last two years, three of them appeared after a few days of rest without feeding reduction. Clinical and haematological examination did not reveal any abnormality. Biochemical examination revealed mild elevation of AST (1374 IU), CK was within normal limits (285 IU). Plasma concentration of vitamin E and whole blood activity of GSH-Px were within normal limits. Biopsy of medial gluteus muscle and its histological examination were performed (H&E, PAS, amylase-PAS). Amylase-PAS reaction revealed amylase resistant polysaccharide granules in muscle fibres. On the basis of histopathology diagnosis of PSSM was established. Grain was withdrawn and feeding with hay was recommended. Because of weight
  • Five years old Quarter Horse mare was presented with a history of repeated attacks of stiffness and dark urine. Onset of clinical signs (back and rear legs stiffness, trembling and sweating) was observed within first 30 minutes of exercise and disappeared within four hours. All attacks were observed during last two years, three of them appeared after a few days of rest without feeding reduction. Clinical and haematological examination did not reveal any abnormality. Biochemical examination revealed mild elevation of AST (1374 IU), CK was within normal limits (285 IU). Plasma concentration of vitamin E and whole blood activity of GSH-Px were within normal limits. Biopsy of medial gluteus muscle and its histological examination were performed (H&E, PAS, amylase-PAS). Amylase-PAS reaction revealed amylase resistant polysaccharide granules in muscle fibres. On the basis of histopathology diagnosis of PSSM was established. Grain was withdrawn and feeding with hay was recommended. Because of weight (en)
Title
  • Clinical management of polysaccharide storage myopathy
  • Clinical management of polysaccharide storage myopathy (en)
  • Klinický management případu polysaccharide storage myopathy (cs)
skos:prefLabel
  • Clinical management of polysaccharide storage myopathy
  • Clinical management of polysaccharide storage myopathy (en)
  • Klinický management případu polysaccharide storage myopathy (cs)
skos:notation
  • RIV/62157124:16170/07:00001588!RIV08-MSM-16170___
http://linked.open...avai/riv/aktivita
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  • Z(MSM6215712403)
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  • 413909
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  • RIV/62157124:16170/07:00001588
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  • glycogen; amylase; rhabdomyolysis (en)
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  • [F5D87D4879BA]
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  • Amsterdam, Netherlands
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  • Jahn, Petr
  • Fictum, Petr
  • Ludvíková, Eva
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  • 16170
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