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  • The role of neutrophil apoptosis in the resolution of bovine mammary gland injury induced by intramammary administration of physiological buffered saline (PBS) or lipopolysaccharide (LPS) was investigated. 1Wenty mammary glands of five non-pregnant heifers were used in the two studies and each animal received both stimuli. Samples of cell populations were collected by mammary gland lavages before and 24, 48, 72 and 96 hours after treatment and examined by light microscopy and staining for myeloperoxidase (MPQ). A marked influx of neutrophils into the mammary gland was observed 24 hours after stimulation. At the same time, apoptotic neutrophils and MPO-positive macrophages (MAC) were identified in the samples. The numbers increased to reach maximum values at 48 hours after stimulation with PBS and at 72 hours after stimulation with LPS. The observed differences in the length of the resolution period indicate that neutrophil viability can be modulated by delaying the apoptotic process.
  • The role of neutrophil apoptosis in the resolution of bovine mammary gland injury induced by intramammary administration of physiological buffered saline (PBS) or lipopolysaccharide (LPS) was investigated. 1Wenty mammary glands of five non-pregnant heifers were used in the two studies and each animal received both stimuli. Samples of cell populations were collected by mammary gland lavages before and 24, 48, 72 and 96 hours after treatment and examined by light microscopy and staining for myeloperoxidase (MPQ). A marked influx of neutrophils into the mammary gland was observed 24 hours after stimulation. At the same time, apoptotic neutrophils and MPO-positive macrophages (MAC) were identified in the samples. The numbers increased to reach maximum values at 48 hours after stimulation with PBS and at 72 hours after stimulation with LPS. The observed differences in the length of the resolution period indicate that neutrophil viability can be modulated by delaying the apoptotic process. (en)
Title
  • Neutrophil apoptosis during the resolution of bovine mammary gland injury
  • Neutrophil apoptosis during the resolution of bovine mammary gland injury (en)
skos:prefLabel
  • Neutrophil apoptosis during the resolution of bovine mammary gland injury
  • Neutrophil apoptosis during the resolution of bovine mammary gland injury (en)
skos:notation
  • RIV/62156489:_____/01:23100005!RIV/2002/MSM/430002/N
http://linked.open.../vavai/riv/strany
  • 41;46
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM 432100001), Z(MZE-M03-99-01)
http://linked.open...iv/cisloPeriodika
  • Februar
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 688692
http://linked.open...ai/riv/idVysledku
  • RIV/62156489:_____/01:23100005
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • apoptosis; bovine mammary gland (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [2616378846DC]
http://linked.open...i/riv/nazevZdroje
  • Research in Veterinary Science
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...ocetUcastnikuAkce
http://linked.open...nichUcastnikuAkce
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 70
http://linked.open...iv/tvurceVysledku
  • Sládek, Zbyšek
http://linked.open...n/vavai/riv/zamer
issn
  • 0034-5228
number of pages
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