About: Voltammetry assay for assessment of oxidative stress linked pathologies in brain tumor suffered childhood patients

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Oxidative stress plays an important role in cancers due to several reasons including metabolism disorder and hypoxia in tissue near the cancer. Numerous researchers have reported participation of oxidative stress in the cancer pathology. However, the mechanism is not well understood. In this study, we investigated oxidative stress development and depletion of antioxidants in blood samples from medulloblastoma, neuroblastoma, glioblastoma and central nervous system cancer suffered childhood patients. The blood samples were analyzed using square wave voltammetry (SWV), dimethyl-4-phenylenediamine method (DMPD), 2'-azinobis 3-ethylbenzothiazoline-6-sulfonic acid (ABTS), free radical method (FR), ferric reducing antioxidant power (FRAP), reduced and oxidized glutathione, and metallothionein. We proved significant correlation between the markers. The findings demonstrate crucial role of oxidative stress and antioxidants levels regulation in the cancer suffered patients. Oxidative stress plays an important role in cancers due to several reasons including metabolism disorder and hypoxia in tissue near the cancer. Numerous researchers have reported participation of oxidative stress in the cancer pathology. However, the mechanism is not well understood. In this study, we investigated oxidative stress development and depletion of antioxidants in blood samples from medulloblastoma, neuroblastoma, glioblastoma and central nervous system cancer suffered childhood patients. The blood samples were analyzed using square wave voltammetry (SWV), dimethyl-4-phenylenediamine method (DMPD), 2'-azinobis 3-ethylbenzothiazoline-6-sulfonic acid (ABTS), free radical method (FR), ferric reducing antioxidant power (FRAP), reduced and oxidized glutathione, and metallothionein. We proved significant correlation between the markers. The findings demonstrate crucial role of oxidative stress and antioxidants levels regulation in the cancer suffered patients. (en)
Title	Voltammetry assay for assessment of oxidative stress linked pathologies in brain tumor suffered childhood patients Voltammetry assay for assessment of oxidative stress linked pathologies in brain tumor suffered childhood patients (en)
skos:prefLabel	Voltammetry assay for assessment of oxidative stress linked pathologies in brain tumor suffered childhood patients Voltammetry assay for assessment of oxidative stress linked pathologies in brain tumor suffered childhood patients (en)
skos:notation	RIV/62156489:43210/12:00199018!RIV13-MSM-43210___
http://linked.open...avai/riv/aktivita	I O P V
http://linked.open...avai/riv/aktivity	I, O, P(ED1.1.00/02.0068), V
http://linked.open...iv/cisloPeriodika	12
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Eckschlager, Tomáš Hynek, David Adam, Vojtěch Masařík, Michal Hubálek, Jaromír Kizek, René Sochor, Jiří Ruttkay-Nedecký, Branislav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Mendelova univerzita v Brně / Agronomická fakulta
http://linked.open...dnocenehoVysledku	178554
http://linked.open...ai/riv/idVysledku	RIV/62156489:43210/12:00199018
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	pathologies; oxidative stress; voltammetry assay (en)
http://linked.open.../riv/klicoveSlovo	pathologies voltammetry assay oxidative stress
http://linked.open...odStatuVydavatele	RS - Srbská republika
http://linked.open...ontrolniKodProRIV	[CF1ECAED571D]
http://linked.open...i/riv/nazevZdroje	International Journal of Electrochemical Science
http://linked.open...in/vavai/riv/obor	CB
http://linked.open...ichTvurcuVysledku	8 (xsd:int)
http://linked.open...cetTvurcuVysledku	11 (xsd:int)
http://linked.open...vavai/riv/projekt	Central european institute of technology
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	7
http://linked.open...iv/tvurceVysledku	Adam, Vojtěch Eckschlager, Tomáš Hubálek, Jaromír Hynek, David Kizek, René Masařík, Michal Pohanka, Miroslav Sochor, Jiří Ruttkay-Nedecký, Branislav Kruseova, J. Kracmarova, Alzbeta
issn	1452-3981
number of pages	15 (xsd:int)
http://localhost/t...ganizacniJednotka	43210

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