About: Genetic diversity of the class II major histocompatibility DRA locus in European, Asiatic and African domestic donkeys

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About: Genetic diversity of the class II major histocompatibility DRA locus in European, Asiatic and African domestic donkeys Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The major histocompatibility complex (MHC) genes coding for antigen presenting molecules are the most polymorphic genes in vertebrate genome. The MHC class II DRA gene shows only small variation in many mammalian species, but it exhibits relatively high level of polymorphism in Equidae, especially in donkeys. This extraordinary degree of polymorphism together with signatures of selection in specific amino acids sites makes the donkey DRA gene a suitable model for population diversity studies. The objective of this study was to investigate the DRA gene diversity in three different populations of donkeys under infectious pressure of protozoan parasites, Theileria equi and Babesia caballi. Three populations of domestic donkeys from Italy (N = 68), Jordan (N = 43), and Kenya (N = 78) were studied. The major histocompatibility complex (MHC) genes coding for antigen presenting molecules are the most polymorphic genes in vertebrate genome. The MHC class II DRA gene shows only small variation in many mammalian species, but it exhibits relatively high level of polymorphism in Equidae, especially in donkeys. This extraordinary degree of polymorphism together with signatures of selection in specific amino acids sites makes the donkey DRA gene a suitable model for population diversity studies. The objective of this study was to investigate the DRA gene diversity in three different populations of donkeys under infectious pressure of protozoan parasites, Theileria equi and Babesia caballi. Three populations of domestic donkeys from Italy (N = 68), Jordan (N = 43), and Kenya (N = 78) were studied. (en)
Title	Genetic diversity of the class II major histocompatibility DRA locus in European, Asiatic and African domestic donkeys Genetic diversity of the class II major histocompatibility DRA locus in European, Asiatic and African domestic donkeys (en)
skos:prefLabel	Genetic diversity of the class II major histocompatibility DRA locus in European, Asiatic and African domestic donkeys Genetic diversity of the class II major histocompatibility DRA locus in European, Asiatic and African domestic donkeys (en)
skos:notation	RIV/62156489:43210/11:00181077!RIV14-MSM-43210___
http://linked.open...avai/riv/aktivita	P S
http://linked.open...avai/riv/aktivity	P(GA523/09/1972), S
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Vrtková, Irena Putnová, Lenka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Mendelova univerzita v Brně / Agronomická fakulta
http://linked.open...dnocenehoVysledku	200995
http://linked.open...ai/riv/idVysledku	RIV/62156489:43210/11:00181077
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Theileria equi; Genetic diversity; Babesia caballi; Domestic donkey; Major histocompatibility class II DRA gene (en)
http://linked.open.../riv/klicoveSlovo	Babesia caballi Domestic donkey Major histocompatibility class II DRA gene Theileria equi Genetic diversity
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[FCC43FD9A6D7]
http://linked.open...i/riv/nazevZdroje	Infection, Genetics and Evolution
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	Comparative immunogenomics of the family Equidae
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	11
http://linked.open...iv/tvurceVysledku	Modrý, David Putnová, Lenka Vrtková, Irena Alloggio, Ingrid Baumeisterova, Aneta Hořín, Petr Qablan, Moneeb Sloboda, Michal Vránová, Marie Vyskočil, Mirko
http://linked.open...ain/vavai/riv/wos	292256800043
issn	1567-1348
number of pages	6 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.meegid.2011.04.010
http://localhost/t...ganizacniJednotka	43210

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