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  • Cancer is presently one of the most studied lifestyle disease. Its treatment is among others based on chemotherapy. One of the drugs used in chemotherapy is doxorubicin, which interacts with DNA and inhibits division of tumour cells. For better usage of this compound as drug, it is necessary to know its interactions with DNA. In work, interactions between doxorubicin and DNA were monitored using electrochemical methods. In addition, intercalation of doxorubicin into DNA isolated from resistant as well as sensitive tumour cells was monitored and mutual correlation was searched
  • Cancer is presently one of the most studied lifestyle disease. Its treatment is among others based on chemotherapy. One of the drugs used in chemotherapy is doxorubicin, which interacts with DNA and inhibits division of tumour cells. For better usage of this compound as drug, it is necessary to know its interactions with DNA. In work, interactions between doxorubicin and DNA were monitored using electrochemical methods. In addition, intercalation of doxorubicin into DNA isolated from resistant as well as sensitive tumour cells was monitored and mutual correlation was searched (en)
Title
  • Monitoring Of DNA-Doxorubicin Interactions by Electrochemical Methods
  • Monitoring Of DNA-Doxorubicin Interactions by Electrochemical Methods (en)
skos:prefLabel
  • Monitoring Of DNA-Doxorubicin Interactions by Electrochemical Methods
  • Monitoring Of DNA-Doxorubicin Interactions by Electrochemical Methods (en)
skos:notation
  • RIV/62156489:43210/10:00184651!RIV12-AV0-43210___
http://linked.open...avai/riv/aktivita
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  • P(GA102/08/1546), P(GAP301/10/0356), P(IAA401990701), P(KAN208130801)
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  • 5
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  • 272477
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  • RIV/62156489:43210/10:00184651
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  • interaction; doxorubicine; electrochemical methods (en)
http://linked.open.../riv/klicoveSlovo
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  • IN - Indická republika
http://linked.open...ontrolniKodProRIV
  • [6F2C36467CBB]
http://linked.open...i/riv/nazevZdroje
  • Journal of Biochemical Technology
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  • 2
http://linked.open...iv/tvurceVysledku
  • Babula, Petr
  • Eckschlager, Tomáš
  • Hubálek, Jaromír
  • Húska, Dalibor
  • Kizek, René
  • Stiborová, Marie
  • Kynclová, Hana
issn
  • 0974-2328
number of pages
http://localhost/t...ganizacniJednotka
  • 43210
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