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  • Tumour markers are biochemical indicators of malignant tumour proliferation. They serve not only for diagnostics of malignant tumour diseases, but also for monitoring of effect of therapy and recurrence of disease. Serum prostate specific antigen (PSA) belongs to group of the best tumor markers, what are available to medicine at the present. In our study the Immune Enzymatic Automated Analyzer AIA 600 II was employed. Calibration curves for PSA and fPSA demonstrates very good linearity by values of R2 = 0.999 in both cases. We assumed to determine levels of PSA in real samples of patients and compare to cell lines. In comparism with non-tumour cell lines we observed the enormous growth of PSA 129-times and fPSA 170-times by RVL-22 and negligible growth for PC-3 cell lines about 2 times. Correlation of obtained data (method PSA2 and method PA) was very close with R2 =0.990.
  • Tumour markers are biochemical indicators of malignant tumour proliferation. They serve not only for diagnostics of malignant tumour diseases, but also for monitoring of effect of therapy and recurrence of disease. Serum prostate specific antigen (PSA) belongs to group of the best tumor markers, what are available to medicine at the present. In our study the Immune Enzymatic Automated Analyzer AIA 600 II was employed. Calibration curves for PSA and fPSA demonstrates very good linearity by values of R2 = 0.999 in both cases. We assumed to determine levels of PSA in real samples of patients and compare to cell lines. In comparism with non-tumour cell lines we observed the enormous growth of PSA 129-times and fPSA 170-times by RVL-22 and negligible growth for PC-3 cell lines about 2 times. Correlation of obtained data (method PSA2 and method PA) was very close with R2 =0.990. (en)
Title
  • Determination of serum prostate specific antigen in patients with tumours of prostate and tumour cell lines
  • Determination of serum prostate specific antigen in patients with tumours of prostate and tumour cell lines (en)
skos:prefLabel
  • Determination of serum prostate specific antigen in patients with tumours of prostate and tumour cell lines
  • Determination of serum prostate specific antigen in patients with tumours of prostate and tumour cell lines (en)
skos:notation
  • RIV/62156489:43210/10:00184606!RIV12-MSM-43210___
http://linked.open...avai/riv/aktivita
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  • 5
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  • 253804
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  • RIV/62156489:43210/10:00184606
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  • prostate-specific antigen; Tumour markers; linearity (en)
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  • IN - Indická republika
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  • [089ED58378C9]
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  • Journal of Biochemical Technology
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  • 2
http://linked.open...iv/tvurceVysledku
  • Babula, Petr
  • Cernei, Natalia Vladimirovna
  • Gumulec, Jaromír
  • Kizek, René
  • Masařík, Michal
  • Zítka, Ondřej
issn
  • 0974-2328
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http://localhost/t...ganizacniJednotka
  • 43210
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