About: Determination of metallothionein, glutathione and termostable protein fraction concentrations in tumour tissue from head and neck area

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About: Determination of metallothionein, glutathione and termostable protein fraction concentrations in tumour tissue from head and neck area Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Tumours of head and neck are one of the most incident tumour diseases. Well-timed diagnosis plays main role in their therapy. Aim of this work consisted in determination of metallothionein (MT), which could be new tumour marker. Determination of its concentration was carried out using electrochemical detection with use of differential pulse voltammetry. Concentrations of MT in samples of denaturized blood plasma of group of patients were about 2.3 uM with slight differences in accordance with localization of tumours. Contents of glutathione and total proteins in denaturized were determined chromatographically and by the help of Biuret reaction. Rate of concentrations levels of GSH/GSSG was varying from 1.31 to 17.66. Tumours of head and neck are one of the most incident tumour diseases. Well-timed diagnosis plays main role in their therapy. Aim of this work consisted in determination of metallothionein (MT), which could be new tumour marker. Determination of its concentration was carried out using electrochemical detection with use of differential pulse voltammetry. Concentrations of MT in samples of denaturized blood plasma of group of patients were about 2.3 uM with slight differences in accordance with localization of tumours. Contents of glutathione and total proteins in denaturized were determined chromatographically and by the help of Biuret reaction. Rate of concentrations levels of GSH/GSSG was varying from 1.31 to 17.66. (en)
Title	Determination of metallothionein, glutathione and termostable protein fraction concentrations in tumour tissue from head and neck area Determination of metallothionein, glutathione and termostable protein fraction concentrations in tumour tissue from head and neck area (en)
skos:prefLabel	Determination of metallothionein, glutathione and termostable protein fraction concentrations in tumour tissue from head and neck area Determination of metallothionein, glutathione and termostable protein fraction concentrations in tumour tissue from head and neck area (en)
skos:notation	RIV/62156489:43210/10:00184598!RIV12-AV0-43210___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(GP301/09/P436), P(KAN208130801)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Majzlík, Petr Cernei, Natalia Vladimirovna Húska, Dalibor Adam, Vojtěch Masařík, Michal Kizek, René Zítka, Ondřej
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Mendelova univerzita v Brně / Agronomická fakulta
http://linked.open...dnocenehoVysledku	253765
http://linked.open...ai/riv/idVysledku	RIV/62156489:43210/10:00184598
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	differential pulse voltammetry; tumor tissue; metallothionein (en)
http://linked.open.../riv/klicoveSlovo	differential pulse voltammetry metallothionein tumor tissue
http://linked.open...odStatuVydavatele	IN - Indická republika
http://linked.open...ontrolniKodProRIV	[D48159298105]
http://linked.open...i/riv/nazevZdroje	Journal of Biochemical Technology
http://linked.open...in/vavai/riv/obor	CB
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Metallothionein analysis in prostate carcinoma at DNA, RNA and protein level. New design and exploiting nanobiosensors and nanosensors to target medicine (NANOSEMED)
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	2
http://linked.open...iv/tvurceVysledku	Adam, Vojtěch Binková, Hana Cernei, Natalia Vladimirovna Húska, Dalibor Kizek, René Majzlík, Petr Masařík, Michal Zítka, Ondřej
issn	0974-2328
number of pages	2 (xsd:int)
http://localhost/t...ganizacniJednotka	43210

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