About: Expression of macrophage CD44 receptor in the course of experimental inflammatory response of bovine mammary gland induced by lipopolysaccharide and muramyl dipeptide

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Expression of macrophage CD44 receptor in the course of experimental inflammatory response of bovine mammary gland induced by lipopolysaccharide and muramyl dipeptide Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The aim of this study was to investigate development over time of the surface expression of CD44 on macrophages during an inflammatory response of bovine mammary gland. Intramammary instillation of muramyl dipeptide (MDP) and lipopolysaccharide (LPS) resulted in a significant increase in the total count of CD44+ non-vacuolized macrophages (NMAC) after 24 hours. During resolution of the inflammatory response, there was observed a gradual decrease in the total count CD44+NMAC. The lower total count and proportion of CD44+ vacuolized macrophages (VMAC) was observed as the effect of MDP and LPS at 24 hours after induction (P<0.01). During resolution, the total count and proportion of CD44+VMAC increased. We have demonstrated CD44 receptor is expressed during the inflammatory response caused by LPS and MDP and the effect of these components on CD44 expression was particularly evident during initiation of the inflammatory response. High expression of CD44 in resolution of inflammatory response may relate to macrophages' involvement in the processes leading to restitution of injured tissues. The aim of this study was to investigate development over time of the surface expression of CD44 on macrophages during an inflammatory response of bovine mammary gland. Intramammary instillation of muramyl dipeptide (MDP) and lipopolysaccharide (LPS) resulted in a significant increase in the total count of CD44+ non-vacuolized macrophages (NMAC) after 24 hours. During resolution of the inflammatory response, there was observed a gradual decrease in the total count CD44+NMAC. The lower total count and proportion of CD44+ vacuolized macrophages (VMAC) was observed as the effect of MDP and LPS at 24 hours after induction (P<0.01). During resolution, the total count and proportion of CD44+VMAC increased. We have demonstrated CD44 receptor is expressed during the inflammatory response caused by LPS and MDP and the effect of these components on CD44 expression was particularly evident during initiation of the inflammatory response. High expression of CD44 in resolution of inflammatory response may relate to macrophages' involvement in the processes leading to restitution of injured tissues. (en)
Title	Expression of macrophage CD44 receptor in the course of experimental inflammatory response of bovine mammary gland induced by lipopolysaccharide and muramyl dipeptide Expression of macrophage CD44 receptor in the course of experimental inflammatory response of bovine mammary gland induced by lipopolysaccharide and muramyl dipeptide (en)
skos:prefLabel	Expression of macrophage CD44 receptor in the course of experimental inflammatory response of bovine mammary gland induced by lipopolysaccharide and muramyl dipeptide Expression of macrophage CD44 receptor in the course of experimental inflammatory response of bovine mammary gland induced by lipopolysaccharide and muramyl dipeptide (en)
skos:notation	RIV/62156489:43210/09:00128002!RIV14-MSM-43210___
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(GA524/03/1531), S, Z(MZE0002716201)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Sládek, Zbyšek
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Mendelova univerzita v Brně / Agronomická fakulta
http://linked.open...dnocenehoVysledku	314417
http://linked.open...ai/riv/idVysledku	RIV/62156489:43210/09:00128002
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	murymyl dipeptide; lipopolysaccharide; inflammatory response; macrophage; CD44 (en)
http://linked.open.../riv/klicoveSlovo	macrophage lipopolysaccharide inflammatory response CD44 murymyl dipeptide
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[4E839328E129]
http://linked.open...i/riv/nazevZdroje	Research in Veterinary Science
http://linked.open...in/vavai/riv/obor	GJ
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	The role of mononuclear phagocytes during the acute inflammation of the bovine mammary gland
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	86
http://linked.open...iv/tvurceVysledku	Ryšánek, Dušan Sládek, Zbyšek
http://linked.open...ain/vavai/riv/wos	264244800009
http://linked.open...n/vavai/riv/zamer	Zdravá zvířata a bezpečné potraviny jako základ pro zdraví lidí
issn	0034-5288
number of pages	6 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.rvsc.2008.07.016
http://localhost/t...ganizacniJednotka	43210

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 32 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software