About: Magnetic and Non-Magnetic Iron-Oxide Deposits in Basal Ganglia     Goto   Sponge   NotDistinct   Permalink

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  • A number of samples extracted from the human brain (basal ganglia) have been investigated by the scanning and transmission electron microscopy (SEM/TEM), SQUID magnetometry, and Mössbauer spectroscopy at ambient and cryogenic temperatures. A considerable amount of biomineralized iron-oxides was found in the extracellular matter. This material refers to perfect single crystals of the size 50 - 1000 nm and the TEM mode, after indexing, allows their identification as magnetite Fe3O4 and/or hematite ?- Fe2O3. The SQUID magnetometry reveals a classification of the samples into three groups: dominating diamagnetism (I), dominating paramagnetism (III), and the intermediate class (II). The magnetic response reflects an overall distribution of nanoparticles of different size and surface/bulk ratio. In class III the bifurcation point of the zero-field-cooled-magnetization and field-cooled-magnetization curves lies above the multicomponent contributions. The registered response is completely different from that measured for the ferritin - an iron storage protein where the ferrihydrite core of 6 nm in size exhibits superparamagnetism with the blocking temperature Tb = 11 K and the critical temperature Tc = 20 K. room temperature and consequently the magnetic hysteresis has been identified even at the room temperature. The shape of the hysteresis loop is complex, owing to the
  • A number of samples extracted from the human brain (basal ganglia) have been investigated by the scanning and transmission electron microscopy (SEM/TEM), SQUID magnetometry, and Mössbauer spectroscopy at ambient and cryogenic temperatures. A considerable amount of biomineralized iron-oxides was found in the extracellular matter. This material refers to perfect single crystals of the size 50 - 1000 nm and the TEM mode, after indexing, allows their identification as magnetite Fe3O4 and/or hematite ?- Fe2O3. The SQUID magnetometry reveals a classification of the samples into three groups: dominating diamagnetism (I), dominating paramagnetism (III), and the intermediate class (II). The magnetic response reflects an overall distribution of nanoparticles of different size and surface/bulk ratio. In class III the bifurcation point of the zero-field-cooled-magnetization and field-cooled-magnetization curves lies above the multicomponent contributions. The registered response is completely different from that measured for the ferritin - an iron storage protein where the ferrihydrite core of 6 nm in size exhibits superparamagnetism with the blocking temperature Tb = 11 K and the critical temperature Tc = 20 K. room temperature and consequently the magnetic hysteresis has been identified even at the room temperature. The shape of the hysteresis loop is complex, owing to the (en)
Title
  • Magnetic and Non-Magnetic Iron-Oxide Deposits in Basal Ganglia
  • Magnetic and Non-Magnetic Iron-Oxide Deposits in Basal Ganglia (en)
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  • Magnetic and Non-Magnetic Iron-Oxide Deposits in Basal Ganglia
  • Magnetic and Non-Magnetic Iron-Oxide Deposits in Basal Ganglia (en)
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  • RIV/61989592:15310/13:33145995!RIV14-MSM-15310___
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  • P(EE2.3.20.0155)
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  • 85698
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  • RIV/61989592:15310/13:33145995
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  • Ganglia; Basal; Deposits; Iron-Oxide; Non-Magnetic; Magnetic (en)
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  • [0C2730CF627C]
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  • New York, US
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  • 12
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  • Horizons in Neuroscience Research
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  • Miglierini, Marcel
  • Boča, Roman
  • Kopáni, Martin
  • Mrázová, Viera
  • Čaplovičová, Mária
  • Dlháň, Ľubomír
number of pages
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  • Nova Science Publishers, Inc.
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  • 978-1-62618-964-5
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  • 15310
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