About: 4-arylazo-3,5-diamino-pyrazole compounds and use thereof

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20130122&DB=EPODOC&locale=en_EP&CC=US&NR=8357673B2&KC=B2&ND=4
Description	A series of mono-and binuclear 4-arylazo-3,5-diamino-pyrazoles which are useful for inhibition of cyclin-dependent kinases (preferably CDK9). Hence they can be used as antimitotic,pro-apoptotitc and antiinflammatory drugs, in particular, in chemotherapy of cancer and asthma, therapy of psoriasis and parasitoses as those caused by fungi or protists, treatment of Alzheimer's disease or as antineurodegenerative drugs, or to suppress immunostimulation. A series of mono-and binuclear 4-arylazo-3,5-diamino-pyrazoles which are useful for inhibition of cyclin-dependent kinases (preferably CDK9). Hence they can be used as antimitotic,pro-apoptotitc and antiinflammatory drugs, in particular, in chemotherapy of cancer and asthma, therapy of psoriasis and parasitoses as those caused by fungi or protists, treatment of Alzheimer's disease or as antineurodegenerative drugs, or to suppress immunostimulation. (en)
Title	4-arylazo-3,5-diamino-pyrazole compounds and use thereof 4-arylazo-3,5-diamino-pyrazole compounds and use thereof (en)
skos:prefLabel	4-arylazo-3,5-diamino-pyrazole compounds and use thereof 4-arylazo-3,5-diamino-pyrazole compounds and use thereof (en)
skos:notation	RIV/61989592:15310/13:33144523!RIV14-MSM-15310___
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM6198959216)
http://linked.open...cisloPatentuVzoru	US8357673
http://linked.open...eleniPatentuVzoru	2013-01-22 (xsd:date)
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Kryštof, Vladimír Strnad, Miroslav Lenobel, René Cankař, Petr
http://linked.open.../riv/druhVysledku	P - Patent
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	119855
http://linked.open...ai/riv/idVysledku	RIV/61989592:15310/13:33144523
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	compounds; 4-arylazo-3,5-diamino-pyrazole (en)
http://linked.open.../riv/klicoveSlovo	4-arylazo-3 5-diamino-pyrazole compounds
http://linked.open...ontrolniKodProRIV	[A7F3705776BB]
http://linked.open.../licencniPoplatek	A - Poskytovatel licence na výsledek požaduje licenční poplatek
http://linked.open...ydaniPatentuVzoru	Alexandria
http://linked.open...atelePatentuVzoru	United States Patent and Trademark Office (USPTO)
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...UplatneniVysledku	2013
http://linked.open...ydaniPatentuVzoru	US - Spojené státy americké
http://linked.open...iv/tvurceVysledku	Kryštof, Vladimír Strnad, Miroslav Cankař, Petr Lenobel, René Fryšová, Iveta Slouka, Jan Fischer, Peter Martin
http://linked.open...mniOchranaPatentu	B - USTPO (Úřad pro patenty a ochranné známky USA)
http://linked.open...avai/riv/vlastnik	Univerzita Palackého v Olomouci
http://linked.open...itiJinymSubjektem	A - Nabytí licence je nutné vždy
http://linked.open...uzitiPatentuVzoru	A - Pouze udělený nebo využívaný pouze vlastníkem
http://linked.open...n/vavai/riv/zamer	Modulation of signalling and regulatory pathways in normal and cancer cells
http://linked.open...stnikPatentuVzoru	Univerzita Palackého v Olomouci
http://localhost/t...ganizacniJednotka	15310

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