About: Antibacterial activity and toxicity of silver

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About: Antibacterial activity and toxicity of silver - Nanosilver versus ionic silver Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The in vitro study of antibacterial activity of silver nanoparticles (NPs), prepared via modified Tollens process, revealed high antibacterial activity even at very low concentrations around several units of mg/L. These concentrations are comparable with concentrations of ionic silver revealing same antibacterial effect. However, such low concentrations of silver NPs did not show acute cytotoxicity to mammalian cells - this occurs at concentrations higher than 60 mg/L of silver, while the cytotoxic level of ionic silver is much more lower (approx. 1 mg/L). Moreover, the silver NPs exhibit lower acute ecotoxicity against the eukaryotic organisms such as Paramecium caudatum, Monoraphidium sp. and D. melanogaster. The silver NPs are toxic to these organisms at the concentrations higher than 30 mg/L of silver. On contrary, ionic silver retains its cytoxicity and ecotoxicity even at the concentration equal to 1 mg/L. The performed experiments demonstrate significantly lower toxicity of silver NPs against the eukaryotic organisms than against the prokaryotic organisms. The in vitro study of antibacterial activity of silver nanoparticles (NPs), prepared via modified Tollens process, revealed high antibacterial activity even at very low concentrations around several units of mg/L. These concentrations are comparable with concentrations of ionic silver revealing same antibacterial effect. However, such low concentrations of silver NPs did not show acute cytotoxicity to mammalian cells - this occurs at concentrations higher than 60 mg/L of silver, while the cytotoxic level of ionic silver is much more lower (approx. 1 mg/L). Moreover, the silver NPs exhibit lower acute ecotoxicity against the eukaryotic organisms such as Paramecium caudatum, Monoraphidium sp. and D. melanogaster. The silver NPs are toxic to these organisms at the concentrations higher than 30 mg/L of silver. On contrary, ionic silver retains its cytoxicity and ecotoxicity even at the concentration equal to 1 mg/L. The performed experiments demonstrate significantly lower toxicity of silver NPs against the eukaryotic organisms than against the prokaryotic organisms. (en)
Title	Antibacterial activity and toxicity of silver - Nanosilver versus ionic silver Antibacterial activity and toxicity of silver - Nanosilver versus ionic silver (en)
skos:prefLabel	Antibacterial activity and toxicity of silver - Nanosilver versus ionic silver Antibacterial activity and toxicity of silver - Nanosilver versus ionic silver (en)
skos:notation	RIV/61989592:15310/11:33118896!RIV12-MSM-15310___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0512), P(ED2.1.00/03.0058), P(GAP304/10/1316), Z(MSM6198959218), Z(MSM6198959223)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Vaníčková, Markéta Soukupová, Jana Panáček, Aleš Kvítek, Libor Prucek, Robert Zbořil, Radek
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	186398
http://linked.open...ai/riv/idVysledku	RIV/61989592:15310/11:33118896
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Silver nanoparticles , antibacterial activity, toxicity, cytotoxicity, ecotoxicity, eukaryotic organisms (en)
http://linked.open.../riv/klicoveSlovo	Silver nanoparticles antibacterial activity cytotoxicity eukaryotic organisms ecotoxicity toxicity
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[D86EF35903A4]
http://linked.open...i/riv/nazevZdroje	Journal of Physics: Conference Series
http://linked.open...in/vavai/riv/obor	JJ
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Research center of powdered nanomaterials Regional Centre of Advanced Technologies and Materials In vitro and in vivo study of antimicrobial activity and toxicity of silver nanoparticles, nanocomposites and materials based on silver nanoparticles
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	304
http://linked.open...iv/tvurceVysledku	Kvítek, Libor Kolář, Milan Panáček, Aleš Prucek, Robert Soukupová, Jana Vaníčková, Markéta Zbořil, Radek
http://linked.open...n/vavai/riv/zamer	Komplexní sloučeniny a oxidy přechodných kovů s využitím v bioaplikacích a nanotechnologiích Nové možnosti diagnostiky a imunomodulace u infekčních onemocnění a imunopatologických stavů
issn	1742-6588
number of pages	8 (xsd:int)
http://bibframe.org/vocab/doi	10.1088/1742-6596/304/1/012029
http://localhost/t...ganizacniJednotka	15310

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