About: Two-dimensional imaging of spontaneous ultra-weak photon emission from the human skin: role of reactive oxygen species

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About: Two-dimensional imaging of spontaneous ultra-weak photon emission from the human skin: role of reactive oxygen species Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In the human skin, reactive oxygen species (ROS) produced continuously during oxidative metabolic processes (cellular respiration, oxidative burst) are essential for various cellular processes such as defense against infection, cellular signaling and apoptosis. On the other hand, when the formation of ROS exceeds a capacity of the non-enzymatic and the enzymatic antioxidant defense system, ROS cause the damage to the human skin known to initiate premature skin aging and skin cancer. In this study, two-dimensional spontaneous ultra-weak photon emission from the human skin has been measured using a highly sensitive charged coupled device (CCD) camera. It is demonstrated here that two-dimensional ultra-weak photon emission from the human skin increases with the topical application of exogenous ROS in the following order: hydrogen peroxide (H2O2) { superoxide anion radical (O2?-) { hydroxyl radical (HO?). We propose here that the two-dimensional ultra-weak photon emission can be used as a non-invasive tool for the spatial and temporal monitoring of oxidative stress in the human skin. In the human skin, reactive oxygen species (ROS) produced continuously during oxidative metabolic processes (cellular respiration, oxidative burst) are essential for various cellular processes such as defense against infection, cellular signaling and apoptosis. On the other hand, when the formation of ROS exceeds a capacity of the non-enzymatic and the enzymatic antioxidant defense system, ROS cause the damage to the human skin known to initiate premature skin aging and skin cancer. In this study, two-dimensional spontaneous ultra-weak photon emission from the human skin has been measured using a highly sensitive charged coupled device (CCD) camera. It is demonstrated here that two-dimensional ultra-weak photon emission from the human skin increases with the topical application of exogenous ROS in the following order: hydrogen peroxide (H2O2) { superoxide anion radical (O2?-) { hydroxyl radical (HO?). We propose here that the two-dimensional ultra-weak photon emission can be used as a non-invasive tool for the spatial and temporal monitoring of oxidative stress in the human skin. (en)
Title	Two-dimensional imaging of spontaneous ultra-weak photon emission from the human skin: role of reactive oxygen species Two-dimensional imaging of spontaneous ultra-weak photon emission from the human skin: role of reactive oxygen species (en)
skos:prefLabel	Two-dimensional imaging of spontaneous ultra-weak photon emission from the human skin: role of reactive oxygen species Two-dimensional imaging of spontaneous ultra-weak photon emission from the human skin: role of reactive oxygen species (en)
skos:notation	RIV/61989592:15310/11:33118536!RIV12-MSM-15310___
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(ED0007/01/01), S, Z(MSM6198959215)
http://linked.open...iv/cisloPeriodika	11-12
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Pospíšil, Pavel Prasad, Ankush
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	236362
http://linked.open...ai/riv/idVysledku	RIV/61989592:15310/11:33118536
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	ultra-weak photon emission.; reactive oxygen species; skin; Two-dimensional CCD imaging (en)
http://linked.open.../riv/klicoveSlovo	ultra-weak photon emission. Two-dimensional CCD imaging skin reactive oxygen species
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[412D0F29AD50]
http://linked.open...i/riv/nazevZdroje	Journal of Biophotonics
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Centre of the Region Haná for Biotechnological and Agricultural Research
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	4
http://linked.open...iv/tvurceVysledku	Pospíšil, Pavel Prasad, Ankush
http://linked.open...ain/vavai/riv/wos	000297740500006
http://linked.open...n/vavai/riv/zamer	Variabilita složek a interakcí v rostlinném patosystému a vliv faktorů prostředí na jejich projev
issn	1864-063X
number of pages	9 (xsd:int)
http://bibframe.org/vocab/doi	10.1002/jbio.201100073
http://localhost/t...ganizacniJednotka	15310

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