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rdf:type
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Description
| - DNA lesions trigger the DNA damage response (DDR) machinery, which protects genomic integrity and sustains cellular survival. Increasing data underline the significance of the integrity of the DDR pathway in chemotherapy response. According to a recent work, persistent exposure of A549 lung carcinoma cells to doxorubicin induces an initial DDR-dependent checkpoint response, followed by a later DDR-independent, but p27Kip1-dependent one.
- DNA lesions trigger the DNA damage response (DDR) machinery, which protects genomic integrity and sustains cellular survival. Increasing data underline the significance of the integrity of the DDR pathway in chemotherapy response. According to a recent work, persistent exposure of A549 lung carcinoma cells to doxorubicin induces an initial DDR-dependent checkpoint response, followed by a later DDR-independent, but p27Kip1-dependent one. (en)
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Title
| - The roles of p27Kip1 and DNA damage signalling in the chemotherapy-induced delayed cell cycle checkpoint
- The roles of p27Kip1 and DNA damage signalling in the chemotherapy-induced delayed cell cycle checkpoint (en)
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skos:prefLabel
| - The roles of p27Kip1 and DNA damage signalling in the chemotherapy-induced delayed cell cycle checkpoint
- The roles of p27Kip1 and DNA damage signalling in the chemotherapy-induced delayed cell cycle checkpoint (en)
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skos:notation
| - RIV/61989592:15310/10:10215636!RIV11-MSM-15310___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15310/10:10215636
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - SKP2; p38-MAPK; p27Kip1; DNA-PKcs; ATR; ATM; chemotherapy; cell cycle arrest; DNA damage response (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Journal of Cellular and Molecular Medicine
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Bártek, Jiří
- Liontos, Michalis
- Angelopoulou, Roxani
- Gorgoulis, Vassilis
- Papavassiliou, Athanasios
- Pateras, Ioannis
- Velimezi, Georgia
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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