About: 3-Hydroxy-2-phenyl-4(1H)-quinolinones as promising biologically active compounds     Goto   Sponge   NotDistinct   Permalink

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  • 2-Phenyl-3-hydroxy-4(1H)-quinolinones can be considered as aza-analogues of flavones, compounds which are known for the wide-range of their biological activity. These quinolinones were studied as inhibitors of topoisomerase, gyrase and IMPDH. They were tested for anticancer activity in-vitro and were also shown to possess immunosuppressive properties. This review is the first summarizing the synthesis and activity of the mentioned quinolinones.
  • 2-Phenyl-3-hydroxy-4(1H)-quinolinones can be considered as aza-analogues of flavones, compounds which are known for the wide-range of their biological activity. These quinolinones were studied as inhibitors of topoisomerase, gyrase and IMPDH. They were tested for anticancer activity in-vitro and were also shown to possess immunosuppressive properties. This review is the first summarizing the synthesis and activity of the mentioned quinolinones. (en)
Title
  • 3-Hydroxy-2-phenyl-4(1H)-quinolinones as promising biologically active compounds
  • 3-Hydroxy-2-phenyl-4(1H)-quinolinones as promising biologically active compounds (en)
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  • 3-Hydroxy-2-phenyl-4(1H)-quinolinones as promising biologically active compounds
  • 3-Hydroxy-2-phenyl-4(1H)-quinolinones as promising biologically active compounds (en)
skos:notation
  • RIV/61989592:15310/09:10214125!RIV11-MSM-15310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(LC07017), S, Z(MSM6198959216), Z(MSM6198959223)
http://linked.open...iv/cisloPeriodika
  • 6
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  • 353927
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  • RIV/61989592:15310/09:10214125
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  • 2-Phenyl-3-hydroxy-4(1H)-quinolinones (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
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  • [8ADA9415CD7C]
http://linked.open...i/riv/nazevZdroje
  • Mini Reviews in Medicinal Chemistry
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  • 9
http://linked.open...iv/tvurceVysledku
  • Hajdúch, Marián
  • Hlaváč, Jan
  • Kolář, Milan
  • Soural, Miroslav
  • Hradil, Pavel
  • Večeřová, Renata
http://linked.open...ain/vavai/riv/wos
  • 000267047200006
http://linked.open...n/vavai/riv/zamer
issn
  • 1389-5575
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  • 15310
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