About: Synthesis of 2-chloro-N,N,N-trialkylethanaminium salts and related hydroxy-analogues as analytical standards for monitoring potential chemical warfare agent precursors

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About: Synthesis of 2-chloro-N,N,N-trialkylethanaminium salts and related hydroxy-analogues as analytical standards for monitoring potential chemical warfare agent precursors Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	A set of choline related derivatives of 2-chloro-N,N,N-trialkylethanaminium salts N-substituted with simple alkyl groups such as methyl, ethyl, n-propyl and isopropyl has been prepared and characterized by the standard methods. Two methodologies based on the alkylation reaction have been developed. The first one utilized the direct alkylation of 2-chloro-N,N-dialkylethanamines to afford the desired aminium salts. In cases where the first method failed the second alternative three-step methodology starting with the alkylation of the 2-(dialkylamino)ethanols was used. All these derivatives can be used as analytical standards for monitoring of potential chemical warfare agent precursors A set of choline related derivatives of 2-chloro-N,N,N-trialkylethanaminium salts N-substituted with simple alkyl groups such as methyl, ethyl, n-propyl and isopropyl has been prepared and characterized by the standard methods. Two methodologies based on the alkylation reaction have been developed. The first one utilized the direct alkylation of 2-chloro-N,N-dialkylethanamines to afford the desired aminium salts. In cases where the first method failed the second alternative three-step methodology starting with the alkylation of the 2-(dialkylamino)ethanols was used. All these derivatives can be used as analytical standards for monitoring of potential chemical warfare agent precursors (en)
Title	Synthesis of 2-chloro-N,N,N-trialkylethanaminium salts and related hydroxy-analogues as analytical standards for monitoring potential chemical warfare agent precursors Synthesis of 2-chloro-N,N,N-trialkylethanaminium salts and related hydroxy-analogues as analytical standards for monitoring potential chemical warfare agent precursors (en)
skos:prefLabel	Synthesis of 2-chloro-N,N,N-trialkylethanaminium salts and related hydroxy-analogues as analytical standards for monitoring potential chemical warfare agent precursors Synthesis of 2-chloro-N,N,N-trialkylethanaminium salts and related hydroxy-analogues as analytical standards for monitoring potential chemical warfare agent precursors (en)
skos:notation	RIV/61989592:15310/09:00010471!RIV10-MSM-15310___
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM6198959216)
http://linked.open...iv/cisloPeriodika	11
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Lemr, Karel Bednář, Petr Maloň, Michal Stýskala, Jakub Cankař, Petr
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	345125
http://linked.open...ai/riv/idVysledku	RIV/61989592:15310/09:00010471
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	2-chloro-N; N; N-trialkylethanaminium salts; chemical warfare agent precursors; alkylation of amines; 2-(dialkylamino)ethanols (en)
http://linked.open.../riv/klicoveSlovo	N 2-(dialkylamino)ethanols 2-chloro-N N-trialkylethanaminium salts alkylation of amines chemical warfare agent precursors
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[61F009A78344]
http://linked.open...i/riv/nazevZdroje	Arkivoc
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	2009
http://linked.open...iv/tvurceVysledku	Bednář, Petr Lemr, Karel Maloň, Michal Cankař, Petr Stýskala, Jakub
http://linked.open...n/vavai/riv/zamer	Modulation of signalling and regulatory pathways in normal and cancer cells
issn	1424-6376
number of pages	13 (xsd:int)
http://localhost/t...ganizacniJednotka	15310

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