About: Initial Study on the Toxicity of Silver Nanoparticles (NPs) against Paramecium caudatum

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In this initial study, the toxicity effect of silver NPs against a model unicellular eukaryotic organism of Paramecium caudatum was studied. For the purpose of this study, a dialysis-based method was adapted, which allowed the preparation of stable aqueous dispersions of silver NPs in various silver concentrations that were necessary for the evaluation of toxicity limits of these particles. The obtained results demonstrate that the silver NPs do not exhibit any toxicity action against the tested unicellular eukaryotic organism below the concentration of 25 mg . L-1 whereas ionic silver retains its toxicity even at a concentration of 0.4 mg . L-1. Such a considerable difference in the toxicity effect of these two forms of silver has not been observed in the previously published study concerning bacteria (Panacek, A.; Kvitek, L.; Prucek, R.; Koldr, M.; Vecefova, R.; Pizurova, N.; Sharma, V. K.; Nevecna, T.; Zboril, R. J. Phys. Chem. B 2006, 110, 16248-16253). Additionally, it was proven that the surfact In this initial study, the toxicity effect of silver NPs against a model unicellular eukaryotic organism of Paramecium caudatum was studied. For the purpose of this study, a dialysis-based method was adapted, which allowed the preparation of stable aqueous dispersions of silver NPs in various silver concentrations that were necessary for the evaluation of toxicity limits of these particles. The obtained results demonstrate that the silver NPs do not exhibit any toxicity action against the tested unicellular eukaryotic organism below the concentration of 25 mg . L-1 whereas ionic silver retains its toxicity even at a concentration of 0.4 mg . L-1. Such a considerable difference in the toxicity effect of these two forms of silver has not been observed in the previously published study concerning bacteria (Panacek, A.; Kvitek, L.; Prucek, R.; Koldr, M.; Vecefova, R.; Pizurova, N.; Sharma, V. K.; Nevecna, T.; Zboril, R. J. Phys. Chem. B 2006, 110, 16248-16253). Additionally, it was proven that the surfact (en)
Title	Initial Study on the Toxicity of Silver Nanoparticles (NPs) against Paramecium caudatum Initial Study on the Toxicity of Silver Nanoparticles (NPs) against Paramecium caudatum (en)
skos:prefLabel	Initial Study on the Toxicity of Silver Nanoparticles (NPs) against Paramecium caudatum Initial Study on the Toxicity of Silver Nanoparticles (NPs) against Paramecium caudatum (en)
skos:notation	RIV/61989592:15310/09:00010354!RIV10-MSM-15310___
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(1M0512), S, Z(MSM0021620822), Z(MSM6198959216), Z(MSM6198959218)
http://linked.open...iv/cisloPeriodika	11
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Vaníčková, Markéta Soukupová, Jana Panáček, Aleš Kvítek, Libor Prucek, Robert Zbořil, Radek Bancířová, Martina Milde, David
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	319569
http://linked.open...ai/riv/idVysledku	RIV/61989592:15310/09:00010354
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	silver nanoparticles; toxicity; Paramecium caudatum (en)
http://linked.open.../riv/klicoveSlovo	Paramecium caudatum toxicity silver nanoparticles
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[FB5FF64B6038]
http://linked.open...i/riv/nazevZdroje	Journal of Physical Chemistry Part C: Nanomaterials and Interfaces
http://linked.open...in/vavai/riv/obor	CF
http://linked.open...ichTvurcuVysledku	8 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	Research center of powdered nanomaterials
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	113
http://linked.open...iv/tvurceVysledku	Dittrich, Milan Kvítek, Libor Panáček, Aleš Prucek, Robert Soukupová, Jana Vaníčková, Markéta Zbořil, Radek Valentová, Eva Bancířová, Martina Milde, David
http://linked.open...n/vavai/riv/zamer	Modulation of signalling and regulatory pathways in normal and cancer cells Komplexní sloučeniny a oxidy přechodných kovů s využitím v bioaplikacích a nanotechnologiích Research of new drug structures
issn	1932-7447
number of pages	5 (xsd:int)
http://localhost/t...ganizacniJednotka	15310

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