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| rdf:type
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| Description
| - Byly připraveny komplexy železa obsahující deriváty od N6-benzyladenosinu o složení [Fe(Ln)Cl3] H2O {L1 = N6-(2-fluorobenzyl)adenosin (1), L2 = N6-(4-fluorobenzyl)adenosin (2), L3 = N6-(2-trifluoromethylbenzyl)adenosin (3), L4 = N6-(3-trifluoromethylbenzyl)adenosin (4), L5 = N6-(4-trifluoromethylbenzyl)adenosin (5), L6 = N6-(4-trifluoromethoxybenzyl)adenosin (6), and L7 = N6-(4-chlorobenzyl)adenosin (7)}. Sloučeniny byly charakterizovány pomocí elementárních analýz, 57Fe Mössbauer. spektroskopie, ES+ MS, FTIR, 1H and 13C NMR spectroskopie, magnetochemického a vodivostního měření, termických (TGA/DSC/DTA) analýz a DFT výpočtů. Sloučeniny byly také testovány pro jejich in vitro cytotoxicitu proti rakovině následujících lidských buněčných linií: maligní melanom (G-361), osteogenní sarkom (HOS), chronická myeloidní leukémie (K-562) a adenokarcinom prsu (MCF-7). (cs)
- Iron complexes (1-7) involving N6-benzyladenosine derivatives of the predominant composition [Fe(Ln)Cl3] center dot H2O {where L1 = N6-(2-fluorobenzyl)adenosine (1), L2 = N6-(4-fluorobenzyl)adenosine (2), L3 = N6-(2-trifluoromethylbenzyl)adenosine (3), L4 = N6-(3-trifluoromethylbenzyl)adenosine (4), L5 = N6-(4-trifluoromethylbenzyl)adenosine (5), L6 = N6-(4-trifluoromethoxybenzyl)adenosine (6), and L7 = N6-(4-chlorobenzyl)adenosine (7)} have been synthesized. The compounds have been characterized by elemental analysis, variable-temperature and in-field 57Fe Mössbauer, ES+ MS, FTIR, 1H and 13C NMR spectroscopies, magnetochemical and conductivity measurements, thermal (TGA/DSC/DTA) analyses, and DFT calculations. It has been found that the organic molecule is coordinated to iron via N7 atom of the appropriate adenosine derivative and the products are represented by mixtures of complexes with various iron oxidation (FeIII/FeII) and spin states (S = 5/2, 4/2, 3/2, 2/2) and geometries (tetrahedral or trigo
- Iron complexes (1-7) involving N6-benzyladenosine derivatives of the predominant composition [Fe(Ln)Cl3] center dot H2O {where L1 = N6-(2-fluorobenzyl)adenosine (1), L2 = N6-(4-fluorobenzyl)adenosine (2), L3 = N6-(2-trifluoromethylbenzyl)adenosine (3), L4 = N6-(3-trifluoromethylbenzyl)adenosine (4), L5 = N6-(4-trifluoromethylbenzyl)adenosine (5), L6 = N6-(4-trifluoromethoxybenzyl)adenosine (6), and L7 = N6-(4-chlorobenzyl)adenosine (7)} have been synthesized. The compounds have been characterized by elemental analysis, variable-temperature and in-field 57Fe Mössbauer, ES+ MS, FTIR, 1H and 13C NMR spectroscopies, magnetochemical and conductivity measurements, thermal (TGA/DSC/DTA) analyses, and DFT calculations. It has been found that the organic molecule is coordinated to iron via N7 atom of the appropriate adenosine derivative and the products are represented by mixtures of complexes with various iron oxidation (FeIII/FeII) and spin states (S = 5/2, 4/2, 3/2, 2/2) and geometries (tetrahedral or trigo (en)
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| Title
| - Novel iron complexes bearing N6-substituted adenosine derivatives: Synthesis, magnetic, 57Fe Mössbauer, DFT, and in vitro cytotoxicity studies
- Novel iron complexes bearing N6-substituted adenosine derivatives: Synthesis, magnetic, 57Fe Mössbauer, DFT, and in vitro cytotoxicity studies (en)
- Nové komplexy železa s N6-substituovanými deriváty adenosinu: Syntéza, magnetické vlastnosti, 57Fe Mössbauerova spektroskopie, DFT a studium in vitro cytotoxicity (cs)
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| skos:prefLabel
| - Novel iron complexes bearing N6-substituted adenosine derivatives: Synthesis, magnetic, 57Fe Mössbauer, DFT, and in vitro cytotoxicity studies
- Novel iron complexes bearing N6-substituted adenosine derivatives: Synthesis, magnetic, 57Fe Mössbauer, DFT, and in vitro cytotoxicity studies (en)
- Nové komplexy železa s N6-substituovanými deriváty adenosinu: Syntéza, magnetické vlastnosti, 57Fe Mössbauerova spektroskopie, DFT a studium in vitro cytotoxicity (cs)
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| skos:notation
| - RIV/61989592:15310/08:00005557!RIV09-MSM-15310___
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15310/08:00005557
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - Iron complexes; Adenosine derivatives; 57Fe Mössbauer spectroscopy; DFT calculations; Cytotoxicity (en)
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| http://linked.open.../riv/klicoveSlovo
| |
| http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - Bioorganic & Medicinal Chemistry
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| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Trávníček, Zdeněk
- Zbořil, Radek
- Popa, Igor
- Čajan, Michal
- Mikulík, Jiří
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
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