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| rdf:type
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| Description
| - Řada čtvercových palladnatých komplexů o složení cis-[Pd(Ln)2Cl2] {L1 = 2-chloro-6-benzylamino-9-izopropylpurin (1), L2 = 2-chloro-6-[(4-methoxybenzyl)amino]-9-izopropylpurin (2), L3 = 2-chloro-6-[(2-methoxybenzyl)amino]-9-izopropylpurin (3) a 2-[(chloropropyl)amino]-6-benzylamino-9-izopropylpurin (6)} byla připravena reakcí PdCl2 s Ln v molárním poměru 1:2. Naopak, stejná reakce následovaná rekrystalizací produktu z N,N'-dimethylformamidu (DMF) vede k trans-[Pd(Ln)Cl2].nDMF {L3, n = 0 (4), n = 1 (4*DMF); L4 = 2-chloro-6-[(2,3-dimethoxybenzyl)-amino]-9-izopropylpurin, n = 0 (5), n = 1.5 (5*DMF). Sloučeniny byly charakterizovány pomocí elementární analýzy, vodivostních měření, 1H a 13C NMR spekter a TGA. Molekulové struktury trans-[Pd(L3)2Cl2] (4) a trans-[Pd(L4)2Cl2] byly určeny pomocí monokrystalové rengenostrukturní analýzy. Všechny komplexy byly testovány na cytotoxicitu. (cs)
- A series os square-planar Pd(II) complexes of the compositions cis-[Pd(Ln)2Cl2] {L1 = 2-chloro-6-benzylamino-9-isopropylpurine (1), L2 = 2-chloro-6-[(4-methoxybenzyl)amino]-9-isopropylpurine (2), L3 = 2-chloro-6-[(2-methoxybenzyl)amino]-9-isopropylpurine (3) and 2-[(chloropropyl)amino]-6-benzylamino-9-isopropylpurine (6)} has been synthesized by the reaction of PdCl2 with Ln in a 1:2 molar ratio. In contrast, the same reaction followed by recrystallization of the product from N,N'-dimethylformamide (DMF) leads to trans-[Pd(Ln)Cl2].nDMF {L3, n = 0 (4), n = 1 (4*DMF); L4 = 2-chloro-6-[(2,3-dimethoxybenzyl)-amino]-9-isopropylpurine, n = 0 (5), n = 1.5 (5*DMF). The compounds have been characterized by elemental analyses, conductivity measurements, 1H and 13C NMR spectra and TGA. The molecular structures of trans-[Pd(L3)2Cl2] (4) and trans-[Pd(L4)2Cl2] have been determined by single crystal X-ray analysis. All the comlexes have been tested for their cytotoxicity.
- A series os square-planar Pd(II) complexes of the compositions cis-[Pd(Ln)2Cl2] {L1 = 2-chloro-6-benzylamino-9-isopropylpurine (1), L2 = 2-chloro-6-[(4-methoxybenzyl)amino]-9-isopropylpurine (2), L3 = 2-chloro-6-[(2-methoxybenzyl)amino]-9-isopropylpurine (3) and 2-[(chloropropyl)amino]-6-benzylamino-9-isopropylpurine (6)} has been synthesized by the reaction of PdCl2 with Ln in a 1:2 molar ratio. In contrast, the same reaction followed by recrystallization of the product from N,N'-dimethylformamide (DMF) leads to trans-[Pd(Ln)Cl2].nDMF {L3, n = 0 (4), n = 1 (4*DMF); L4 = 2-chloro-6-[(2,3-dimethoxybenzyl)-amino]-9-isopropylpurine, n = 0 (5), n = 1.5 (5*DMF). The compounds have been characterized by elemental analyses, conductivity measurements, 1H and 13C NMR spectra and TGA. The molecular structures of trans-[Pd(L3)2Cl2] (4) and trans-[Pd(L4)2Cl2] have been determined by single crystal X-ray analysis. All the comlexes have been tested for their cytotoxicity. (en)
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| Title
| - Synthesis, characterization and assesment of the cytotoxic properties of cis- and trans-[Pd(L)2Cl2] complexes involving 6-benzylamino-9-isopropylpurine derivates
- Syntéza, charakteristika a určení cytotoxické aktivity komplexů cis- a trans-[Pd(L)2Cl2], které obsahují deriváty 6-benzylamino-9-izopropylpurinu (cs)
- Synthesis, characterization and assesment of the cytotoxic properties of cis- and trans-[Pd(L)2Cl2] complexes involving 6-benzylamino-9-isopropylpurine derivates (en)
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| skos:prefLabel
| - Synthesis, characterization and assesment of the cytotoxic properties of cis- and trans-[Pd(L)2Cl2] complexes involving 6-benzylamino-9-isopropylpurine derivates
- Syntéza, charakteristika a určení cytotoxické aktivity komplexů cis- a trans-[Pd(L)2Cl2], které obsahují deriváty 6-benzylamino-9-izopropylpurinu (cs)
- Synthesis, characterization and assesment of the cytotoxic properties of cis- and trans-[Pd(L)2Cl2] complexes involving 6-benzylamino-9-isopropylpurine derivates (en)
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| skos:notation
| - RIV/61989592:15310/07:00004496!RIV08-MSM-15310___
|
| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
| - P(GA203/04/1168), Z(MSM6198959218)
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
| |
| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
| |
| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
| |
| http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15310/07:00004496
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| http://linked.open...riv/jazykVysledku
| |
| http://linked.open.../riv/klicovaSlova
| - palladium(II) complexes; 6-benzylamino-9-isopropylpurine derivates; cytotoxicity; X-ray structure analysis (en)
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| http://linked.open.../riv/klicoveSlovo
| |
| http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - Journal of Inorganic Biochemistry
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| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
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| http://linked.open...vavai/riv/projekt
| |
| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Trávníček, Zdeněk
- Popa, Igor
- SzÜčová, Lucie
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
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