About: Cisatracurium vs. Rocuronium: A prospective, comparative, randomized study in adult patients under total intravenous anaesthesia.     Goto   Sponge   NotDistinct   Permalink

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Description
  • Jsou prezentovány porovnávací studie u dospělých pacientů při úplné vnitrožilní anestezii (cs)
  • To compare the pharmacodynamics of cisatracurium and rocuronium-induced neuromuscular block following single dose, allowing either spontaneous or neostigmine-accelerated complete recovery. Methods: Following the ethics committee approval and informed consent, 120 patients scheduled for elective surgery under TIVA with tracheal intubation were randomized into 4 groups with different cisatracurium (CIS, 0.10 or 0.15 mg.kg-1) or rocuronium (ROC, 0.60 or 0.90 mg.kg-1) doses administered. For each patient, the onset time for 95 % depression of T1, clinical duration until 25 % recovery, recovery index (T1 from 25 to 75 %) and time from T1 25 % to TOF-ratio 0.9 were determined allowing either spontaneous or induced recovery. Results: The onset times were 277 (SD 58), 220 (46), 91 (16) and 77 (16) s for the CIS 0.10, CIS 0.15, ROC 0.60 and ROC 0.90 groups (p < 0.05), respectively, with lower variability in both ROC groups (p < 0.05). The clinical durations were 42 (7), 52 (7), 35 (11) and 52 (12) min, r
  • To compare the pharmacodynamics of cisatracurium and rocuronium-induced neuromuscular block following single dose, allowing either spontaneous or neostigmine-accelerated complete recovery. Methods: Following the ethics committee approval and informed consent, 120 patients scheduled for elective surgery under TIVA with tracheal intubation were randomized into 4 groups with different cisatracurium (CIS, 0.10 or 0.15 mg.kg-1) or rocuronium (ROC, 0.60 or 0.90 mg.kg-1) doses administered. For each patient, the onset time for 95 % depression of T1, clinical duration until 25 % recovery, recovery index (T1 from 25 to 75 %) and time from T1 25 % to TOF-ratio 0.9 were determined allowing either spontaneous or induced recovery. Results: The onset times were 277 (SD 58), 220 (46), 91 (16) and 77 (16) s for the CIS 0.10, CIS 0.15, ROC 0.60 and ROC 0.90 groups (p < 0.05), respectively, with lower variability in both ROC groups (p < 0.05). The clinical durations were 42 (7), 52 (7), 35 (11) and 52 (12) min, r (en)
Title
  • Cisatracurium vs. Rocuronium: A prospective, comparative, randomized study in adult patients under total intravenous anaesthesia.
  • Cisatracurium vs. Rocuronium: A prospective, comparative, randomized study in adult patients under total intravenous anaesthesia. (en)
  • Cisatracurium vs. Rocuronium: A porovnávací studie u dospělých pacientů při úplné vnitrožilní anestezii (cs)
skos:prefLabel
  • Cisatracurium vs. Rocuronium: A prospective, comparative, randomized study in adult patients under total intravenous anaesthesia.
  • Cisatracurium vs. Rocuronium: A prospective, comparative, randomized study in adult patients under total intravenous anaesthesia. (en)
  • Cisatracurium vs. Rocuronium: A porovnávací studie u dospělých pacientů při úplné vnitrožilní anestezii (cs)
skos:notation
  • RIV/61989592:15310/06:00002878!RIV07-MZ0-15310___
http://linked.open.../vavai/riv/strany
  • 333-338
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(ND7665)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 468789
http://linked.open...ai/riv/idVysledku
  • RIV/61989592:15310/06:00002878
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Cisatracurium; Rocuronium; anaesthesia. (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [3EC4E449921A]
http://linked.open...i/riv/nazevZdroje
  • Biomedical Papers
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 150
http://linked.open...iv/tvurceVysledku
  • Bělohlávek, Radim
  • Koutná, Jiřina
  • Janásková, E.
  • Vujčíková, M.
issn
  • 1213-8118
number of pages
http://localhost/t...ganizacniJednotka
  • 15310
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