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Description
| - Je popsána příprava, spektrální a magnetické vlastnosti a studium in vitro cytotoxické aktivity kobaltnatých komplexů s cytokininovými deriváty: struktura monohydrátu chloridu 6-(3-methoxybenzylamino)purinia. (cs)
- Cobalt(II) complexes with 6-(2-hydroxybenzylamino)purine (HL1), 6-(2-methoxybenzylaminopurine (HL2), 6-(3-methoxybenzylamino)purine (HL3) and 6-(4/methoxybenzylamino)purine (HL4) of the composition [Co(L1)Cl(H2O)2].H2O (1), [Co(L2)Cl(H2O)2] (2), [Co(L3)2(H2O)2].2H2O (3), [Co(L4)2(H2O)2].2H2O (4) have been synthesized. The compounds have been characterized by elemental analysis, FT-IR, ES+MS (electrospray mass spectra in the positive ion mode) and electronic spectroscopies, magnetic and conductivity data as tetrahedral high-spin cobalt(II) complexes. The thermal stability of the complexes has also been studied. The cytotoxicity of the complexes (1-4) was determined by a Calcein acetoxymethyl (AM) assay. Human malignant melanoma (G361), human chronic myelogenous erythroleukemia (K562), human osteogenic sarcoma (HOS) and human breast adenocarcinoma (MCF7) cell lines were used for the testing. The molecular structure of 6-(3-methoxybenzylamino)purinium chloride monohydrate H2L3+.Cl-.H2O i.e. a protonated
- Cobalt(II) complexes with 6-(2-hydroxybenzylamino)purine (HL1), 6-(2-methoxybenzylaminopurine (HL2), 6-(3-methoxybenzylamino)purine (HL3) and 6-(4/methoxybenzylamino)purine (HL4) of the composition [Co(L1)Cl(H2O)2].H2O (1), [Co(L2)Cl(H2O)2] (2), [Co(L3)2(H2O)2].2H2O (3), [Co(L4)2(H2O)2].2H2O (4) have been synthesized. The compounds have been characterized by elemental analysis, FT-IR, ES+MS (electrospray mass spectra in the positive ion mode) and electronic spectroscopies, magnetic and conductivity data as tetrahedral high-spin cobalt(II) complexes. The thermal stability of the complexes has also been studied. The cytotoxicity of the complexes (1-4) was determined by a Calcein acetoxymethyl (AM) assay. Human malignant melanoma (G361), human chronic myelogenous erythroleukemia (K562), human osteogenic sarcoma (HOS) and human breast adenocarcinoma (MCF7) cell lines were used for the testing. The molecular structure of 6-(3-methoxybenzylamino)purinium chloride monohydrate H2L3+.Cl-.H2O i.e. a protonated (en)
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Title
| - Synthesis, spectral, magnetic and in vitro cytotoxic activity studies of cobalt(II) complexes with cytokinin derivates: X-ray structure of 6-(3-methoxybenzylamino)purinium chloride monohydrate
- Synthesis, spectral, magnetic and in vitro cytotoxic activity studies of cobalt(II) complexes with cytokinin derivates: X-ray structure of 6-(3-methoxybenzylamino)purinium chloride monohydrate (en)
- Příprava, spektrální a magnetické vlastnosti a studium in vitro cytotoxické aktivity kobaltnatých komplexů s cytokininovými deriváty: struktura monohydrátu chloridu 6-(3-methoxybenzylamino)purinia (cs)
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skos:prefLabel
| - Synthesis, spectral, magnetic and in vitro cytotoxic activity studies of cobalt(II) complexes with cytokinin derivates: X-ray structure of 6-(3-methoxybenzylamino)purinium chloride monohydrate
- Synthesis, spectral, magnetic and in vitro cytotoxic activity studies of cobalt(II) complexes with cytokinin derivates: X-ray structure of 6-(3-methoxybenzylamino)purinium chloride monohydrate (en)
- Příprava, spektrální a magnetické vlastnosti a studium in vitro cytotoxické aktivity kobaltnatých komplexů s cytokininovými deriváty: struktura monohydrátu chloridu 6-(3-methoxybenzylamino)purinia (cs)
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skos:notation
| - RIV/61989592:15310/05:00001885!RIV06-MSM-15310___
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GA203/04/1168), Z(MSM6198959218)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15310/05:00001885
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - cobalt(II); cytokinin derivates; cytotoxity; spectral study; magnetic study (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Journal of Inorganic Biochemistry
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Rolčík, Jakub
- Trávníček, Zdeněk
- Popa, Igor
- Klanicová, Alena
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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