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Description
  • Naše hledání přirozeně se vyskytujících aromatických cytokininů v rostlinách vedlo v poslední době k objevu několika nových látek povahy rostlinných hormonů-methoxybenzylaminopurinů (Tarkowská et al., 2003). Následně byla připravena skupina jejich syntetických analog a charakterizována metodami MS, NMR a rentgenové difrakce. Byla zkoumána jejich biologická aktivita po různých stránkách (efekt cytokininů in vitro stejně jako experimenty ve volném poli, protinádorové vlastnosti, apod.). Aby bylo možné studovat tyto zajímavé sloučeniny podrobněji, byla vyvinuta rovněž rychlá a velmi účinná metoda pro jejich izolaci ze složitých biologických směsí (krev, rostlinný extrakt) založená na imunoafinitní chromatografii. (cs)
  • Our search for naturally occurring aromatic cytokinins in plants led recently to the discovery of several new plant hormone substances # methoxybenzylaminopurines. Subsequently, a group of their synthetic analogues has been prepared and characterized by MS, NMR and X-ray diffraction methods. Various aspects of their biological activity (cytokinin effect studied in-vitro as well as in field experiments, anti-cancer properties etc.) have been investigated. To study these interesting compounds in more details, rapid and highly efficient method for their isolation from complex biological matrices (blood, plant extract), based on immunoaffinity chromatography, has also been developed.
  • Our search for naturally occurring aromatic cytokinins in plants led recently to the discovery of several new plant hormone substances # methoxybenzylaminopurines. Subsequently, a group of their synthetic analogues has been prepared and characterized by MS, NMR and X-ray diffraction methods. Various aspects of their biological activity (cytokinin effect studied in-vitro as well as in field experiments, anti-cancer properties etc.) have been investigated. To study these interesting compounds in more details, rapid and highly efficient method for their isolation from complex biological matrices (blood, plant extract), based on immunoaffinity chromatography, has also been developed. (en)
Title
  • Methoxybenzylaminopuriny - nová endogenní třída cytokininů (cs)
  • Methoxybenzylaminopurines - new endogenous class of cytokinins
  • Methoxybenzylaminopurines - new endogenous class of cytokinins (en)
skos:prefLabel
  • Methoxybenzylaminopuriny - nová endogenní třída cytokininů (cs)
  • Methoxybenzylaminopurines - new endogenous class of cytokinins
  • Methoxybenzylaminopurines - new endogenous class of cytokinins (en)
skos:notation
  • RIV/61989592:15310/04:00002396!RIV/2005/GA0/153105/N
http://linked.open.../vavai/riv/strany
  • 85
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA522/01/0275)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 573157
http://linked.open...ai/riv/idVysledku
  • RIV/61989592:15310/04:00002396
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Cytokinins;synthesis;biological activity;mass spectrometry (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [E2133922AF2E]
http://linked.open...i/riv/mistoVydani
  • Canberra
http://linked.open...i/riv/nazevZdroje
  • 18th IPGSA conference, Conference Handbook
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Doležal, Karel
  • Strnad, Miroslav
  • Tarkowská, Danuše
  • Trávníček, Zdeněk
  • Popa, Igor
  • Hauserová, Eva
  • Hradecká, Veronika
number of pages
http://purl.org/ne...btex#hasPublisher
  • Australian National University
http://localhost/t...ganizacniJednotka
  • 15310
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