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  • New series of cytokinins derived from 6-benzylaminopurine (BAP) have been developed for agricultural and biotechnological applications. These compounds exhibit very high biological activities in different cytokinin bioassays. Preferentially, the methoxy and fluoro derivatives had 2-10 times higher activity then trans-zeatin and expressed very positive antisenescent and morphogenetic properties in different in vitro cultures of some horticulture species. These compounds have been recently identified as new natural cytokinins. Our research focused on the primary mechanism of action of plant hormones cytokinins in cell division cycle has showed that natural plant cytokinins are rather non-specific inhibitors of various protein kinases. Surprisingly, among aromatic cytokinin derivatives, we have discovered a compound, 2-(2-hydroxyethylamino)-6-benzylamino-9-methylpurine, named %22olomoucine%22, which specifically inhibits some cyclin-dependent kinases (cdks) at micromolar concentration. One of the inhibit
  • New series of cytokinins derived from 6-benzylaminopurine (BAP) have been developed for agricultural and biotechnological applications. These compounds exhibit very high biological activities in different cytokinin bioassays. Preferentially, the methoxy and fluoro derivatives had 2-10 times higher activity then trans-zeatin and expressed very positive antisenescent and morphogenetic properties in different in vitro cultures of some horticulture species. These compounds have been recently identified as new natural cytokinins. Our research focused on the primary mechanism of action of plant hormones cytokinins in cell division cycle has showed that natural plant cytokinins are rather non-specific inhibitors of various protein kinases. Surprisingly, among aromatic cytokinin derivatives, we have discovered a compound, 2-(2-hydroxyethylamino)-6-benzylamino-9-methylpurine, named %22olomoucine%22, which specifically inhibits some cyclin-dependent kinases (cdks) at micromolar concentration. One of the inhibit (en)
Title
  • Cytokinins in biotechnology and medicine
  • Cytokinins in biotechnology and medicine (en)
skos:prefLabel
  • Cytokinins in biotechnology and medicine
  • Cytokinins in biotechnology and medicine (en)
skos:notation
  • RIV/61989592:15310/03:00001597!RIV/2004/GA0/153104/N
http://linked.open.../vavai/riv/strany
  • 168
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA522/03/0323)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 602577
http://linked.open...ai/riv/idVysledku
  • RIV/61989592:15310/03:00001597
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Cytokinins, biotechnology, medicine (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [F65E5334FB77]
http://linked.open...v/mistoKonaniAkce
  • Zagreb
http://linked.open...i/riv/mistoVydani
  • Zagreb
http://linked.open...i/riv/nazevZdroje
  • 2nd Symposium of the Croatian Society on Plant Physiology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...ocetUcastnikuAkce
http://linked.open...nichUcastnikuAkce
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Strnad, Miroslav
http://linked.open...vavai/riv/typAkce
number of pages
http://purl.org/ne...btex#hasPublisher
  • Coratian Biological Society
http://localhost/t...ganizacniJednotka
  • 15310
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