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  • Cellular redox phenomena are involved in numerous biochemical pathways and play a key role in many pathological events and clinical situations. The overall oxidation/reduction (redox) state present in biological compartments is a major target for possible pharmaceutical intervention and, consequently, the processes associated with its change have attracted increased attention in recent years. This overview describes the methods for evaluating the concentrations of redox active compounds and their redox activity and the methods for evaluating the overall biological fluids and tissues redox capacity, with a focus on the redox potential parameter, its modulation, its measurement, and its importance for diagnosis and treatment. Examples of voltammetric measurement of reducing power profiles of biological tissues and fluids in healthy and disease states are discussed.
  • Cellular redox phenomena are involved in numerous biochemical pathways and play a key role in many pathological events and clinical situations. The overall oxidation/reduction (redox) state present in biological compartments is a major target for possible pharmaceutical intervention and, consequently, the processes associated with its change have attracted increased attention in recent years. This overview describes the methods for evaluating the concentrations of redox active compounds and their redox activity and the methods for evaluating the overall biological fluids and tissues redox capacity, with a focus on the redox potential parameter, its modulation, its measurement, and its importance for diagnosis and treatment. Examples of voltammetric measurement of reducing power profiles of biological tissues and fluids in healthy and disease states are discussed. (en)
Title
  • Biological redox activity: Its importance, methods for its quantification and implication for health and disease
  • Biological redox activity: Its importance, methods for its quantification and implication for health and disease (en)
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  • Biological redox activity: Its importance, methods for its quantification and implication for health and disease
  • Biological redox activity: Its importance, methods for its quantification and implication for health and disease (en)
skos:notation
  • RIV/61989592:15310/00:00000991!RIV/2001/MSM/153101/N
http://linked.open.../vavai/riv/strany
  • 516
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM 153100007)
http://linked.open...iv/cisloPeriodika
  • 3-4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
  • Hrbáč, Jan
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 705734
http://linked.open...ai/riv/idVysledku
  • RIV/61989592:15310/00:00000991
http://linked.open...riv/jazykVysledku
http://linked.open...ontrolniKodProRIV
  • [B8AA7E22BA9E]
http://linked.open...i/riv/nazevZdroje
  • Drug Development Research
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 50
http://linked.open...iv/tvurceVysledku
  • Hrbáč, Jan
  • Kohen, R.
http://linked.open...n/vavai/riv/zamer
issn
  • 0272-4391
number of pages
http://localhost/t...ganizacniJednotka
  • 15310
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