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rdfs:seeAlso
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Description
| - Overexpression of transcription factors RUNX1 and NF-E2 was reported in granulocytes of patients with polycythemia vera and other myeloproliferative neoplasms (MPN). We report that RUNX1 and NF-E2 overexpression is not specific for MPN because it was not detected in patients with EPO receptor (EPOR) mutations, suggesting distinct mechanisms by which erythroid progenitors in polycythemias with defects of hypoxia sensing and EPOR mutations exert their EPO-hypersensitivity.
- Overexpression of transcription factors RUNX1 and NF-E2 was reported in granulocytes of patients with polycythemia vera and other myeloproliferative neoplasms (MPN). We report that RUNX1 and NF-E2 overexpression is not specific for MPN because it was not detected in patients with EPO receptor (EPOR) mutations, suggesting distinct mechanisms by which erythroid progenitors in polycythemias with defects of hypoxia sensing and EPOR mutations exert their EPO-hypersensitivity. (en)
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Title
| - RUNX1 and NF-E2 upregulation is not specific for MPNs, but is seen in polycythemic disorders with augmented HIF signaling
- RUNX1 and NF-E2 upregulation is not specific for MPNs, but is seen in polycythemic disorders with augmented HIF signaling (en)
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skos:prefLabel
| - RUNX1 and NF-E2 upregulation is not specific for MPNs, but is seen in polycythemic disorders with augmented HIF signaling
- RUNX1 and NF-E2 upregulation is not specific for MPNs, but is seen in polycythemic disorders with augmented HIF signaling (en)
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skos:notation
| - RIV/61989592:15110/14:33151198!RIV15-MSM-15110___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(EE2.3.20.0164), P(EE2.3.30.0041), P(GAP305/11/1745), S
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15110/14:33151198
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - transcription factors; NF-E2; RUNX1; polycythemia (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Divoký, Vladimír
- Horváthová, Monika
- Kapraľová, Katarína
- Prchal, Josef T.
- Lorenzo, Felipe
- Láníková, Lucie
- Song, Jihyun
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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http://bibframe.org/vocab/doi
| - 10.1182/blood-2013-10-534222
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http://localhost/t...ganizacniJednotka
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