About: Key tumor suppressor genes inactivated by %22greater promoter%22 methylation and somatic mutations in head and neck cancer     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:seeAlso
Description
  • Tumor suppressor genes (TSGs) are commonly inactivated by somatic mutation and/or promoter methylation; yet., recent high-throughput genomic studies have not identified key TSGs inactivated by both mechanisms. We pursued an integrated molecular analysis based on methylation binding domain sequencing (MBD-seq), 450K Methylation arrays, whole exome sequencing, and whole genome gene expression arrays in primary head and neck squamous cell carcinoma (HNSCC) tumors and matched uvulopalatopharyngoplasty tissue samples (UPPPs).
  • Tumor suppressor genes (TSGs) are commonly inactivated by somatic mutation and/or promoter methylation; yet., recent high-throughput genomic studies have not identified key TSGs inactivated by both mechanisms. We pursued an integrated molecular analysis based on methylation binding domain sequencing (MBD-seq), 450K Methylation arrays, whole exome sequencing, and whole genome gene expression arrays in primary head and neck squamous cell carcinoma (HNSCC) tumors and matched uvulopalatopharyngoplasty tissue samples (UPPPs). (en)
Title
  • Key tumor suppressor genes inactivated by %22greater promoter%22 methylation and somatic mutations in head and neck cancer
  • Key tumor suppressor genes inactivated by %22greater promoter%22 methylation and somatic mutations in head and neck cancer (en)
skos:prefLabel
  • Key tumor suppressor genes inactivated by %22greater promoter%22 methylation and somatic mutations in head and neck cancer
  • Key tumor suppressor genes inactivated by %22greater promoter%22 methylation and somatic mutations in head and neck cancer (en)
skos:notation
  • RIV/61989592:15110/14:33149294!RIV15-MSM-15110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I
http://linked.open...iv/cisloPeriodika
  • 7
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 24211
http://linked.open...ai/riv/idVysledku
  • RIV/61989592:15110/14:33149294
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • somatic mutations, integration analysis; DNA methylation; Tumor Suppressor Genes; Head and Neck Squamous Cell Carcinoma (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [5DA234B3F92F]
http://linked.open...i/riv/nazevZdroje
  • Epigenetics
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 9
http://linked.open...iv/tvurceVysledku
  • Žižková, Veronika
  • Agrawal, Nishant
  • Califano, Joseph
  • Fertig, Elana
  • Frederick, Mitchell
  • Guerrero-Preston, Rafael
  • Hadar, Tal
  • Koch, Wayne
  • Marchionni, Luigi
  • Michailidi, Christina
  • Myers, Jeffrey
  • Noordhuis, Maartje
  • Pickering, Curtis
  • Sidransky, David
  • Velculescu, Victor
  • Westra, William
  • Yegnasubramanian, Srinivasan
http://linked.open...ain/vavai/riv/wos
  • 000338429500012
issn
  • 1559-2294
number of pages
http://bibframe.org/vocab/doi
  • 10.4161/epi.29025
http://localhost/t...ganizacniJednotka
  • 15110
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software