About: 2-[18F]fl uoro-2-deoxy- D -glucose positron emission tomography/ computed tomography examination in patients with chronic lymphocytic leukemia may reveal Richter transformation     Goto   Sponge   NotDistinct   Permalink

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  • The signifi cance of positron emission tomography/computed tomography (PET/CT) in chronic lymphocytic leukemia (CLL) has not yet been systematically studied. This prospective study was aimed at assessing the benefi t of PET/CT in patients with newly diagnosed or relapsed CLL and Richter transformation (RT). PET/CT examination was performed in 23 patients with newly diagnosed disease, 13 with relapsed disease and eight with suspected or histopathologically confi rmed RT. In all patients, the maximum standardized uptake value (SUV max ) was calculated. The median SUV max was 3.4 (range: 1.5 - 6.3) and 3.1 (range: 1.2 - 5.9) in newly diagnosed and relapsed patients, respectively. The median SUV max of patients with suspected or confi rmed RT reached 16.5 (range: 7.2 - 25.3), a value diff erent from that of the previous groups ( p 0.001). 2-[18F]fl uoro- 2-deoxy- D -glucose ( 18 F-FDG) PET/CT revealed infl ammatory lesions in seven patients (16%) and synchronous tumors in two newly diagnosed patients. 18 F-FDG PET/CT may be a benefi cial imaging method when used in individuals with CLL and suspected RT.
  • The signifi cance of positron emission tomography/computed tomography (PET/CT) in chronic lymphocytic leukemia (CLL) has not yet been systematically studied. This prospective study was aimed at assessing the benefi t of PET/CT in patients with newly diagnosed or relapsed CLL and Richter transformation (RT). PET/CT examination was performed in 23 patients with newly diagnosed disease, 13 with relapsed disease and eight with suspected or histopathologically confi rmed RT. In all patients, the maximum standardized uptake value (SUV max ) was calculated. The median SUV max was 3.4 (range: 1.5 - 6.3) and 3.1 (range: 1.2 - 5.9) in newly diagnosed and relapsed patients, respectively. The median SUV max of patients with suspected or confi rmed RT reached 16.5 (range: 7.2 - 25.3), a value diff erent from that of the previous groups ( p 0.001). 2-[18F]fl uoro- 2-deoxy- D -glucose ( 18 F-FDG) PET/CT revealed infl ammatory lesions in seven patients (16%) and synchronous tumors in two newly diagnosed patients. 18 F-FDG PET/CT may be a benefi cial imaging method when used in individuals with CLL and suspected RT. (en)
Title
  • 2-[18F]fl uoro-2-deoxy- D -glucose positron emission tomography/ computed tomography examination in patients with chronic lymphocytic leukemia may reveal Richter transformation
  • 2-[18F]fl uoro-2-deoxy- D -glucose positron emission tomography/ computed tomography examination in patients with chronic lymphocytic leukemia may reveal Richter transformation (en)
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  • 2-[18F]fl uoro-2-deoxy- D -glucose positron emission tomography/ computed tomography examination in patients with chronic lymphocytic leukemia may reveal Richter transformation
  • 2-[18F]fl uoro-2-deoxy- D -glucose positron emission tomography/ computed tomography examination in patients with chronic lymphocytic leukemia may reveal Richter transformation (en)
skos:notation
  • RIV/61989592:15110/14:33145755!RIV15-MSM-15110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • S
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
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http://linked.open...dnocenehoVysledku
  • 58177
http://linked.open...ai/riv/idVysledku
  • RIV/61989592:15110/14:33145755
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • solid tumor; Richter transformation; standardized uptake value; computed tomography; positron emission tomography; chronic lymphocytic leukemia (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [53F1D22D5B96]
http://linked.open...i/riv/nazevZdroje
  • Leukemia & Lymphoma
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 55
http://linked.open...iv/tvurceVysledku
  • Indrák, Karel
  • Jarošová, Marie
  • Procházka, Vít
  • Papajík, Tomáš
  • Flodr, Patrik
  • Buriánková, Eva
  • Henzlová, Lenka
  • Mysliveček, Miroslav
  • Formánek, Radim
  • Kapitáňová, Zuzana
  • Urbanová, Renata
  • Turcsányi, Peter
issn
  • 1042-8194
number of pages
http://bibframe.org/vocab/doi
  • 10.3109/10428194.2013.802313
http://localhost/t...ganizacniJednotka
  • 15110
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