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  • Abstract AIM: To find out whether it is possible to anaesthetize patients safely without analgesia and sedation, using burst pacing prolonged until the patient becomes unconscious. METHODS: One hundred and four patients undergoing implantation or reimplantation of a cardioverter-defibrillator were included. Patients randomized into Group B underwent prolonged burst pacing without analgesia and sedation. Patients in Group T underwent a T-wave shock under analgesia and sedation. Blood samples for measurement of serum neuron-specific enolase were taken before surgery and 6, 24, and 48 h after the procedure. RESULTS: From the 104 patients, 51 were randomly assigned to Group B and 53 to Group T. Four patients from Group B were switched to Group T (ventricular fibrillation not induced by burst pacing). The clinical characteristics of both groups were similar. The mean total time of cardiac arrest was significantly longer in Group B (23.0 +- 4.4 s, median 22.7) vs. Group T (10.3 +- 3.0 s, median 10.0), P { 0.0001 (Mann-Whitney U-test). The effectiveness of both induction methods was similar (92.1% in Group B and 100% in Group T). The mean neuron-specific enolase levels after 6, 24, and 48 h were similar in Groups B and T (13.1 +- 6.3 and 11.6 +- 5.8 mg/L, 14.5 +- 7.5 and 13.4 +- 6.0 mg/L, and 14.9 +- 5.9 and 12.2 +- 6.0 mg/L, respectively) as were these levels compared with baseline neuron-specificenolase levels (14.0 +- 5.9 and 13.4 +- 4.0 mg/L, respectively), P = NS for all. CONCLUSION: Despite a longer time of total cardiac arrest, prolonged burst pacing appears to be a safe and effective method for induction of ventricular fibrillation during cardioverter-defibrillator testing, which enables omission of analgesia and sedation or general anaesthesia. PMID: 23089188 [PubMed - indexed for MEDLINE] Free full text
  • Abstract AIM: To find out whether it is possible to anaesthetize patients safely without analgesia and sedation, using burst pacing prolonged until the patient becomes unconscious. METHODS: One hundred and four patients undergoing implantation or reimplantation of a cardioverter-defibrillator were included. Patients randomized into Group B underwent prolonged burst pacing without analgesia and sedation. Patients in Group T underwent a T-wave shock under analgesia and sedation. Blood samples for measurement of serum neuron-specific enolase were taken before surgery and 6, 24, and 48 h after the procedure. RESULTS: From the 104 patients, 51 were randomly assigned to Group B and 53 to Group T. Four patients from Group B were switched to Group T (ventricular fibrillation not induced by burst pacing). The clinical characteristics of both groups were similar. The mean total time of cardiac arrest was significantly longer in Group B (23.0 +- 4.4 s, median 22.7) vs. Group T (10.3 +- 3.0 s, median 10.0), P { 0.0001 (Mann-Whitney U-test). The effectiveness of both induction methods was similar (92.1% in Group B and 100% in Group T). The mean neuron-specific enolase levels after 6, 24, and 48 h were similar in Groups B and T (13.1 +- 6.3 and 11.6 +- 5.8 mg/L, 14.5 +- 7.5 and 13.4 +- 6.0 mg/L, and 14.9 +- 5.9 and 12.2 +- 6.0 mg/L, respectively) as were these levels compared with baseline neuron-specificenolase levels (14.0 +- 5.9 and 13.4 +- 4.0 mg/L, respectively), P = NS for all. CONCLUSION: Despite a longer time of total cardiac arrest, prolonged burst pacing appears to be a safe and effective method for induction of ventricular fibrillation during cardioverter-defibrillator testing, which enables omission of analgesia and sedation or general anaesthesia. PMID: 23089188 [PubMed - indexed for MEDLINE] Free full text (en)
Title
  • Prolonged burst as a new method for cardioverter-defibrillator testing
  • Prolonged burst as a new method for cardioverter-defibrillator testing (en)
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  • Prolonged burst as a new method for cardioverter-defibrillator testing
  • Prolonged burst as a new method for cardioverter-defibrillator testing (en)
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  • RIV/61989592:15110/13:33147552!RIV14-MSM-15110___
http://linked.open...avai/riv/aktivita
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  • I
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  • 1
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  • 100283
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  • RIV/61989592:15110/13:33147552
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  • testing; cardioverter-defibrillator; method; new; burst; Prolonged (en)
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  • GB - Spojené království Velké Británie a Severního Irska
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  • [565FF40ABE55]
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  • Europace
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  • 15
http://linked.open...iv/tvurceVysledku
  • Fedorco, Marián
  • Táborský, Miloš
  • Zapletalová, Jana
  • Schneiderka, Petr
  • Bulava, Alan
  • Marek, Dan
  • Lukl, Jan
http://linked.open...ain/vavai/riv/wos
  • 000312642400014
issn
  • 1099-5129
number of pages
http://bibframe.org/vocab/doi
  • 10.1093/europace/eus250
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  • 15110
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