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| - Abstract AIM: To find out whether it is possible to anaesthetize patients safely without analgesia and sedation, using burst pacing prolonged until the patient becomes unconscious. METHODS: One hundred and four patients undergoing implantation or reimplantation of a cardioverter-defibrillator were included. Patients randomized into Group B underwent prolonged burst pacing without analgesia and sedation. Patients in Group T underwent a T-wave shock under analgesia and sedation. Blood samples for measurement of serum neuron-specific enolase were taken before surgery and 6, 24, and 48 h after the procedure. RESULTS: From the 104 patients, 51 were randomly assigned to Group B and 53 to Group T. Four patients from Group B were switched to Group T (ventricular fibrillation not induced by burst pacing). The clinical characteristics of both groups were similar. The mean total time of cardiac arrest was significantly longer in Group B (23.0 +- 4.4 s, median 22.7) vs. Group T (10.3 +- 3.0 s, median 10.0), P { 0.0001 (Mann-Whitney U-test). The effectiveness of both induction methods was similar (92.1% in Group B and 100% in Group T). The mean neuron-specific enolase levels after 6, 24, and 48 h were similar in Groups B and T (13.1 +- 6.3 and 11.6 +- 5.8 mg/L, 14.5 +- 7.5 and 13.4 +- 6.0 mg/L, and 14.9 +- 5.9 and 12.2 +- 6.0 mg/L, respectively) as were these levels compared with baseline neuron-specificenolase levels (14.0 +- 5.9 and 13.4 +- 4.0 mg/L, respectively), P = NS for all. CONCLUSION: Despite a longer time of total cardiac arrest, prolonged burst pacing appears to be a safe and effective method for induction of ventricular fibrillation during cardioverter-defibrillator testing, which enables omission of analgesia and sedation or general anaesthesia. PMID: 23089188 [PubMed - indexed for MEDLINE] Free full text
- Abstract AIM: To find out whether it is possible to anaesthetize patients safely without analgesia and sedation, using burst pacing prolonged until the patient becomes unconscious. METHODS: One hundred and four patients undergoing implantation or reimplantation of a cardioverter-defibrillator were included. Patients randomized into Group B underwent prolonged burst pacing without analgesia and sedation. Patients in Group T underwent a T-wave shock under analgesia and sedation. Blood samples for measurement of serum neuron-specific enolase were taken before surgery and 6, 24, and 48 h after the procedure. RESULTS: From the 104 patients, 51 were randomly assigned to Group B and 53 to Group T. Four patients from Group B were switched to Group T (ventricular fibrillation not induced by burst pacing). The clinical characteristics of both groups were similar. The mean total time of cardiac arrest was significantly longer in Group B (23.0 +- 4.4 s, median 22.7) vs. Group T (10.3 +- 3.0 s, median 10.0), P { 0.0001 (Mann-Whitney U-test). The effectiveness of both induction methods was similar (92.1% in Group B and 100% in Group T). The mean neuron-specific enolase levels after 6, 24, and 48 h were similar in Groups B and T (13.1 +- 6.3 and 11.6 +- 5.8 mg/L, 14.5 +- 7.5 and 13.4 +- 6.0 mg/L, and 14.9 +- 5.9 and 12.2 +- 6.0 mg/L, respectively) as were these levels compared with baseline neuron-specificenolase levels (14.0 +- 5.9 and 13.4 +- 4.0 mg/L, respectively), P = NS for all. CONCLUSION: Despite a longer time of total cardiac arrest, prolonged burst pacing appears to be a safe and effective method for induction of ventricular fibrillation during cardioverter-defibrillator testing, which enables omission of analgesia and sedation or general anaesthesia. PMID: 23089188 [PubMed - indexed for MEDLINE] Free full text (en)
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Title
| - Prolonged burst as a new method for cardioverter-defibrillator testing
- Prolonged burst as a new method for cardioverter-defibrillator testing (en)
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skos:prefLabel
| - Prolonged burst as a new method for cardioverter-defibrillator testing
- Prolonged burst as a new method for cardioverter-defibrillator testing (en)
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skos:notation
| - RIV/61989592:15110/13:33147552!RIV14-MSM-15110___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15110/13:33147552
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - testing; cardioverter-defibrillator; method; new; burst; Prolonged (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Fedorco, Marián
- Táborský, Miloš
- Zapletalová, Jana
- Schneiderka, Petr
- Bulava, Alan
- Marek, Dan
- Lukl, Jan
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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http://bibframe.org/vocab/doi
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http://localhost/t...ganizacniJednotka
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