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  • The aim of this study was to investigate the prognostic significance of fourteen anticancer drug-relevant solute carrier transporters (SLCs) in pancreatic cancer in the context of clinical-pathological characteristics and the KRAS mutation status of tumors. Tumors and non-neoplastic pancreatic tissues were obtained from 32 histologically verified patients with pancreatic ductal adenocarcinoma. The transcript profile of SLCs was assessed using quantitative real-time PCR. KRAS mutations in exon 2 were assessed by high-resolution melting analysis and confirmed by sequencing.
  • The aim of this study was to investigate the prognostic significance of fourteen anticancer drug-relevant solute carrier transporters (SLCs) in pancreatic cancer in the context of clinical-pathological characteristics and the KRAS mutation status of tumors. Tumors and non-neoplastic pancreatic tissues were obtained from 32 histologically verified patients with pancreatic ductal adenocarcinoma. The transcript profile of SLCs was assessed using quantitative real-time PCR. KRAS mutations in exon 2 were assessed by high-resolution melting analysis and confirmed by sequencing. (en)
Title
  • The associastion between the expression of solute carrier transporters and the prognosis of pancreatic cancer
  • The associastion between the expression of solute carrier transporters and the prognosis of pancreatic cancer (en)
skos:prefLabel
  • The associastion between the expression of solute carrier transporters and the prognosis of pancreatic cancer
  • The associastion between the expression of solute carrier transporters and the prognosis of pancreatic cancer (en)
skos:notation
  • RIV/61989592:15110/13:33145222!RIV14-MSM-15110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 62332
http://linked.open...ai/riv/idVysledku
  • RIV/61989592:15110/13:33145222
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • KRAS; Survival; Gene expression; SLC transporters; Pancreatic cancer (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [E15E60235442]
http://linked.open...i/riv/nazevZdroje
  • Cancer Chemotherapy and Pharmacology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 72
http://linked.open...iv/tvurceVysledku
  • Honsová, Eva
  • Hlavsa, Jan
  • Kala, Zdeněk
  • Kočík, Matěj
  • Melichar, Bohuslav
  • Oliverius, Martin
  • Souček, Pavel
  • Brynychová, Veronika
  • Hlaváč, Viktor
  • Mazanec, Jan
  • Mohelníková Duchoňová, Beatrice
issn
  • 0344-5704
number of pages
http://bibframe.org/vocab/doi
  • 10.1007/s00280-013-2246-2
http://localhost/t...ganizacniJednotka
  • 15110
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