| Attributes | Values |
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| rdf:type
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| Description
| - The Digital Ulcers Outcome (DUO) Registry was designed to describe the clinical and antibody characteristics, disease course and outcomes of patients with digital ulcers associated with systemic sclerosis (SSc). The DUO Registry is a European, prospective, multicentre, observational, registry of SSc patients with ongoing digital ulcers disease, irrespective of treatment regimen. Data collected included demographics, SSc duration, SSc subset, internal organ manifestations, autoantibodies, previous and ongoing interventions and complications related to didital ulcers. Up to 19 Novečmber 2010 a total of 2439 patients had enrolled into the registry. Most were classified as either limited cutaneous SSc (IcSSc; 52,2%) of diffuse cutaneous SSc (DcSSc; 36,9%).Digital ulcers developer earlier in patients with dcSSc compared with IcSSc. Almost all patients (95.7%) tested positive for antinuclear antibodies, 45,2% for anti-scleroderma-70 and 43,6% for anticentromere antibodies (ACA). The first digital ulcer in the anti-scleroderma-70-positive patient cohort occurred approximately 5 years earlier than the ACA-positive patient group. This study provedes data from a large cohort of SSc patients with a history of digital ulcers. The early occurrence and high frequency of digital ulcer complications are especially seen in patients with dcSSc and/or anti-scleroderma-70 antibodies.
- The Digital Ulcers Outcome (DUO) Registry was designed to describe the clinical and antibody characteristics, disease course and outcomes of patients with digital ulcers associated with systemic sclerosis (SSc). The DUO Registry is a European, prospective, multicentre, observational, registry of SSc patients with ongoing digital ulcers disease, irrespective of treatment regimen. Data collected included demographics, SSc duration, SSc subset, internal organ manifestations, autoantibodies, previous and ongoing interventions and complications related to didital ulcers. Up to 19 Novečmber 2010 a total of 2439 patients had enrolled into the registry. Most were classified as either limited cutaneous SSc (IcSSc; 52,2%) of diffuse cutaneous SSc (DcSSc; 36,9%).Digital ulcers developer earlier in patients with dcSSc compared with IcSSc. Almost all patients (95.7%) tested positive for antinuclear antibodies, 45,2% for anti-scleroderma-70 and 43,6% for anticentromere antibodies (ACA). The first digital ulcer in the anti-scleroderma-70-positive patient cohort occurred approximately 5 years earlier than the ACA-positive patient group. This study provedes data from a large cohort of SSc patients with a history of digital ulcers. The early occurrence and high frequency of digital ulcer complications are especially seen in patients with dcSSc and/or anti-scleroderma-70 antibodies. (en)
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| Title
| - Demographic, clinical and antibody characteristics of patients with digital ulcers in systemic sclerosis: data from the DUO Registry
- Demographic, clinical and antibody characteristics of patients with digital ulcers in systemic sclerosis: data from the DUO Registry (en)
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| skos:prefLabel
| - Demographic, clinical and antibody characteristics of patients with digital ulcers in systemic sclerosis: data from the DUO Registry
- Demographic, clinical and antibody characteristics of patients with digital ulcers in systemic sclerosis: data from the DUO Registry (en)
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| skos:notation
| - RIV/61989592:15110/12:33152304!RIV15-MSM-15110___
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15110/12:33152304
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - DUO Registry; systemic sclerosis; digital ulcers (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - Annals of the Rheumatic Diseases
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| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Smržová, Andrea
- Guillevin, Loic
- Denton, Christopher
- Krieg, Thomas
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| issn
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| number of pages
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| http://bibframe.org/vocab/doi
| - 10.1136/annrheumdis-2011-200631
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| http://localhost/t...ganizacniJednotka
| |
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