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| rdf:type
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| Description
| - To determine the extent of vancomycin removal and vancomycin pharmacokinetics in septic patients with AKI using daily hemodialysis with polysulphone high-flux and low-flux membrane. Five patients received 6 h daily dialysis with low-flux polysulphone membrane, four patients with high-flux polysulphone membrane. Vancomycin was administered over the last hour of dialysis. The maintenance dose was adjusted based on pre-hemodialysis serum concentrations. Patients were followed up for two days. Median percentage of vancomycin removal by low-flux membrane dialysis was 17% (8 - 38%) and by high-flux membrane dialysis was 31% (13-43%). Vancomycin clearance was only moderately higher in high-flux membrane dialysis (median 3.01 l/h, range 2.34-3.5 l/h) compared to low-flux dialysis (median 2.48 l/h, range 0.53-5.68 l/h) in the first day of the study. About two-fold higher vancomycin clearance in high-flux dialysis (median 3.62 l/h, range 1.37-5.07 l/h) was observed on the second day of the study than low-flux dialysis (median 1.74 l/h, range 0.75-30.94 l/h). Both high-flux and low-flux membrane dialysis remove considerable amounts of vancomycin in critically ill septic patients with AKI. Application of vancomycin after each dialysis was required to maintain therapeutic concentrations.
- To determine the extent of vancomycin removal and vancomycin pharmacokinetics in septic patients with AKI using daily hemodialysis with polysulphone high-flux and low-flux membrane. Five patients received 6 h daily dialysis with low-flux polysulphone membrane, four patients with high-flux polysulphone membrane. Vancomycin was administered over the last hour of dialysis. The maintenance dose was adjusted based on pre-hemodialysis serum concentrations. Patients were followed up for two days. Median percentage of vancomycin removal by low-flux membrane dialysis was 17% (8 - 38%) and by high-flux membrane dialysis was 31% (13-43%). Vancomycin clearance was only moderately higher in high-flux membrane dialysis (median 3.01 l/h, range 2.34-3.5 l/h) compared to low-flux dialysis (median 2.48 l/h, range 0.53-5.68 l/h) in the first day of the study. About two-fold higher vancomycin clearance in high-flux dialysis (median 3.62 l/h, range 1.37-5.07 l/h) was observed on the second day of the study than low-flux dialysis (median 1.74 l/h, range 0.75-30.94 l/h). Both high-flux and low-flux membrane dialysis remove considerable amounts of vancomycin in critically ill septic patients with AKI. Application of vancomycin after each dialysis was required to maintain therapeutic concentrations. (en)
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| Title
| - Vancomycin removal during low-flux and high-flux extended daily hemodialysis in critically ill septic patients
- Vancomycin removal during low-flux and high-flux extended daily hemodialysis in critically ill septic patients (en)
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| skos:prefLabel
| - Vancomycin removal during low-flux and high-flux extended daily hemodialysis in critically ill septic patients
- Vancomycin removal during low-flux and high-flux extended daily hemodialysis in critically ill septic patients (en)
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| skos:notation
| - RIV/61989592:15110/12:33138910!RIV13-MZ0-15110___
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15110/12:33138910
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - vancomycin; sepsis; polysulphone membrane; low-flux; high-flux; hemodialysis; acute kidney injury (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - Biomedical Papers-Olomouc
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...vavai/riv/projekt
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Martínek, Arnošt
- Urbánek, Karel
- Brozmanová, Hana
- Grundmann, Milan
- Zahálková, Jana
- Petejová, Naděžda
- Kacířová, Ivana
- Ďuricová, Jana
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| issn
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| number of pages
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| http://bibframe.org/vocab/doi
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| http://localhost/t...ganizacniJednotka
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