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  • First, there are shortly described some theoretical aspects of gas chromatography in two dimensions and some metabolomics fundamentals in the chapter. Following you can find there the section comparing two mostly used derivatization techniques in metabolomics - silylation and indirect alkylation via chloroformiates. Below you can find there 4 experiments describing the experiences of our laboratory in the field of comprehensive two-dimensional gas chromatography human metabolomic analyses - analysis of urine acidic extract in relation to organic acidurias, comparison of harvesting methods for adherently growing human skin fibroblasts (trypsin treatment vs. methanolic quenching), following the discovering the effect of chemoterapeutuc drug 5-fluorouracil to their metabolome, and finally analysis of human blood plasma in relation to metabolic disorders again.
  • First, there are shortly described some theoretical aspects of gas chromatography in two dimensions and some metabolomics fundamentals in the chapter. Following you can find there the section comparing two mostly used derivatization techniques in metabolomics - silylation and indirect alkylation via chloroformiates. Below you can find there 4 experiments describing the experiences of our laboratory in the field of comprehensive two-dimensional gas chromatography human metabolomic analyses - analysis of urine acidic extract in relation to organic acidurias, comparison of harvesting methods for adherently growing human skin fibroblasts (trypsin treatment vs. methanolic quenching), following the discovering the effect of chemoterapeutuc drug 5-fluorouracil to their metabolome, and finally analysis of human blood plasma in relation to metabolic disorders again. (en)
Title
  • Comprehensive Two-dimensional Gas Chromatography Coupled to Time-of-Flight Mass Spectrometry in Human Metabolomics
  • Comprehensive Two-dimensional Gas Chromatography Coupled to Time-of-Flight Mass Spectrometry in Human Metabolomics (en)
skos:prefLabel
  • Comprehensive Two-dimensional Gas Chromatography Coupled to Time-of-Flight Mass Spectrometry in Human Metabolomics
  • Comprehensive Two-dimensional Gas Chromatography Coupled to Time-of-Flight Mass Spectrometry in Human Metabolomics (en)
skos:notation
  • RIV/61989592:15110/12:33138538!RIV13-MSM-15110___
http://linked.open...avai/riv/aktivita
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  • P(ED0030/01/01)
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  • 128254
http://linked.open...ai/riv/idVysledku
  • RIV/61989592:15110/12:33138538
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  • fibroblasts; plasma; urine; metabolomics; Comprehensive two-dimensional gas chromatography (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [8B9E00774065]
http://linked.open...i/riv/mistoVydani
  • Rijeka, Croatia
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  • neuveden
http://linked.open...i/riv/nazevZdroje
  • Gas Chromatography - Biochemicals, Narcotics and Essential Oils
http://linked.open...in/vavai/riv/obor
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  • Adam, Tomáš
  • Bruheim, Per
  • Dostálová, Eva
  • Wojtowicz, Petr
  • Zrostlíková, Jitka
  • Šťastná, Veronika
  • Žídková, Lenka
number of pages
http://bibframe.org/vocab/doi
  • 10.5772/33252
http://purl.org/ne...btex#hasPublisher
  • In Tech
https://schema.org/isbn
  • 978-953-51-0295-3
http://localhost/t...ganizacniJednotka
  • 15110
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