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  • Aim. Provide an overview of how bipolar disorder affects cognitive function in patients. Methods. MEDLINE and PsycInfo data bases were searched for articles indexed by the combinations of MESH term or key word %22bipolar disorder%22 with the following terms: %22cognition%22, %22memory%22, %22neuropsychology%22, %22neuropsychological tests%22, %22lithium%22, %22anticonvulsants%22, %22antipsychotics%22, and %22schizophrenia%22. Constraints limiting time period of publications or their language were not applied. Reference lists of publications identified by these procedures were hand-searched for additional relevant citations. Results. There is evidence of stable and lasting cognitive impairment in all phases of bipolar disorder, including the remission phase, particularly in the following domains: sustained attention, memory and executive functions. But research on the cognitive functions has yielded inconsistent results over recent years. There is a growing need for clarification regarding the magnitude, clinical relevance and confounding variables of cognitive impairment in bipolar patients. The impact of bipolar illness on cognition can be influenced by age of onset, pharmacological treatments, individual response, familial risk factors, and clinical features. In addition to the mood state, cognitive performance in bipolar patients is influenced by seasonality.
  • Aim. Provide an overview of how bipolar disorder affects cognitive function in patients. Methods. MEDLINE and PsycInfo data bases were searched for articles indexed by the combinations of MESH term or key word %22bipolar disorder%22 with the following terms: %22cognition%22, %22memory%22, %22neuropsychology%22, %22neuropsychological tests%22, %22lithium%22, %22anticonvulsants%22, %22antipsychotics%22, and %22schizophrenia%22. Constraints limiting time period of publications or their language were not applied. Reference lists of publications identified by these procedures were hand-searched for additional relevant citations. Results. There is evidence of stable and lasting cognitive impairment in all phases of bipolar disorder, including the remission phase, particularly in the following domains: sustained attention, memory and executive functions. But research on the cognitive functions has yielded inconsistent results over recent years. There is a growing need for clarification regarding the magnitude, clinical relevance and confounding variables of cognitive impairment in bipolar patients. The impact of bipolar illness on cognition can be influenced by age of onset, pharmacological treatments, individual response, familial risk factors, and clinical features. In addition to the mood state, cognitive performance in bipolar patients is influenced by seasonality. (en)
Title
  • COGNITIVE IMPAIRMENT IN BIPOLAR DISORDER
  • COGNITIVE IMPAIRMENT IN BIPOLAR DISORDER (en)
skos:prefLabel
  • COGNITIVE IMPAIRMENT IN BIPOLAR DISORDER
  • COGNITIVE IMPAIRMENT IN BIPOLAR DISORDER (en)
skos:notation
  • RIV/61989592:15110/11:33145491!RIV14-MZ0-15110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(NT11047), V
http://linked.open...iv/cisloPeriodika
  • 1
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http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 190791
http://linked.open...ai/riv/idVysledku
  • RIV/61989592:15110/11:33145491
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Quality of life; Cognitive tests; Mood stabilizers; Genetics; Cognitive impairment; Bipolar disorder (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [6BE2FC61580E]
http://linked.open...i/riv/nazevZdroje
  • Biomedical Papers-Olomouc
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 155
http://linked.open...iv/tvurceVysledku
  • Divéky, Tomáš
  • Látalová, Klára
  • Praško Pavlov, Ján
  • Velartová, Hana
issn
  • 1213-8118
number of pages
http://localhost/t...ganizacniJednotka
  • 15110
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