About: Detection and clinical importance of minimal residual disease in patients with lung cancer

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Lung cancer is one of the leading causes of cancer death and has become an increasingly urgent worldwide health problem (incidence in men 34.01100 000, in women 13.61100 000; mortality in men 29.3/100 000, in women 11.0/1 00 000) (globocan.iarc. fr, 2008). Mortality is increasingly associated with distant metastases development. The minimal residual disease (MRD) in solid tumours means the presence of occult tumour cells in the body of a patient who has undergone curative surgery and has no timher clinical signs of the disease. These isolated occult tumour cells are considered to be the precursors of micrometastases. The MRD testing in lung cancer patients can eliminate complicated surgical procedures in patients with systemic molecular dissemination of the disease and can improve the prognosis. The aim of our pilot study was to establish and validate PCR-based method for MRD testing in lung cancer using different molecular markers. Lung cancer is one of the leading causes of cancer death and has become an increasingly urgent worldwide health problem (incidence in men 34.01100 000, in women 13.61100 000; mortality in men 29.3/100 000, in women 11.0/1 00 000) (globocan.iarc. fr, 2008). Mortality is increasingly associated with distant metastases development. The minimal residual disease (MRD) in solid tumours means the presence of occult tumour cells in the body of a patient who has undergone curative surgery and has no timher clinical signs of the disease. These isolated occult tumour cells are considered to be the precursors of micrometastases. The MRD testing in lung cancer patients can eliminate complicated surgical procedures in patients with systemic molecular dissemination of the disease and can improve the prognosis. The aim of our pilot study was to establish and validate PCR-based method for MRD testing in lung cancer using different molecular markers. (en)
Title	Detection and clinical importance of minimal residual disease in patients with lung cancer - a pilot study Detection and clinical importance of minimal residual disease in patients with lung cancer - a pilot study (en)
skos:prefLabel	Detection and clinical importance of minimal residual disease in patients with lung cancer - a pilot study Detection and clinical importance of minimal residual disease in patients with lung cancer - a pilot study (en)
skos:notation	RIV/61989592:15110/11:10224852!RIV12-MZ0-15110___
http://linked.open...avai/riv/aktivita	P S
http://linked.open...avai/riv/aktivity	P(ED0030/01/01), P(EE2.3.09.0089), P(NS10285), S
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	RADOVÁ, Lenka Szkorupa, Marek BENEDÍKOVÁ, Andrea SROVNAL, Josef KLEIN, Jiří SKALICKÝ, Pavel Hajdúch, Marián
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Lékařská fakulta
http://linked.open...dnocenehoVysledku	193682
http://linked.open...ai/riv/idVysledku	RIV/61989592:15110/11:10224852
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	cancer; lung; MRD (en)
http://linked.open.../riv/klicoveSlovo	cancer MRD lung
http://linked.open...ontrolniKodProRIV	[2C56E786850A]
http://linked.open...v/mistoKonaniAkce	Hradec Králové
http://linked.open...i/riv/mistoVydani	Praha
http://linked.open...i/riv/nazevZdroje	New Frontiers in the Research of PhD Students. Conference of Medical Schools.
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Biomedicine for regional development and human resources Educational support of molecular oncology researchers Clinical significance of minimal residual disease in patients with operable lung cancer
http://linked.open...UplatneniVysledku	2011
http://linked.open...iv/tvurceVysledku	RADOVÁ, Lenka BENEDÍKOVÁ, Andrea HAJDÚCH, Marián KLEIN, Jiří SKALICKÝ, Pavel SROVNAL, Josef SZKORUPA, Marek VAHALÍKOVÁ, M.
http://linked.open...vavai/riv/typAkce	EUR - Evropská
http://linked.open.../riv/zahajeniAkce	2011-11-10 (xsd:date)
number of pages	4 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Univerzita Karlova v Praze
https://schema.org/isbn	978-80-260-0922-1
http://localhost/t...ganizacniJednotka	15110

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