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Description
  • Schizophrenia is a complex, multifactorial psychiatric disorder. Our previous findings indicated that altered functional activity of the complement system, a major mediator of the immune response, is implicated in the pathogenesis of schizophrenia. In order to explore whether these alterations are genetically determined or not, in the present study we evaluated the possible association of complement C1Q component gene variants with susceptibility to schizophrenia in Armenian population, focusing on four frequent single nucleotide polymorphisms (SNPs) of C1QA and C1QB genes.
  • Schizophrenia is a complex, multifactorial psychiatric disorder. Our previous findings indicated that altered functional activity of the complement system, a major mediator of the immune response, is implicated in the pathogenesis of schizophrenia. In order to explore whether these alterations are genetically determined or not, in the present study we evaluated the possible association of complement C1Q component gene variants with susceptibility to schizophrenia in Armenian population, focusing on four frequent single nucleotide polymorphisms (SNPs) of C1QA and C1QB genes. (en)
Title
  • Association of C1QB gene polymorphism with schizophrenia in Armenian population
  • Association of C1QB gene polymorphism with schizophrenia in Armenian population (en)
skos:prefLabel
  • Association of C1QB gene polymorphism with schizophrenia in Armenian population
  • Association of C1QB gene polymorphism with schizophrenia in Armenian population (en)
skos:notation
  • RIV/61989592:15110/11:10224237!RIV12-MSM-15110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • S, Z(MSM6198959205)
http://linked.open...iv/cisloPeriodika
  • 126
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 187328
http://linked.open...ai/riv/idVysledku
  • RIV/61989592:15110/11:10224237
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Armenian population; schizophrenia; C1QB gene polymorphism (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [3F8EB35267B8]
http://linked.open...i/riv/nazevZdroje
  • BMC Medical Genetics
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 12
http://linked.open...iv/tvurceVysledku
  • Arakelyan, Arsen
  • Boyajyan, Anna
  • Gevorgyan, Anaida
  • Khoyetsyan, Aren
  • Mrázek, František
  • Petřek, Martin
  • Sťahelová, Anna
  • Zakharyan, Roksana
http://linked.open...n/vavai/riv/zamer
issn
  • 1471-2350
number of pages
http://localhost/t...ganizacniJednotka
  • 15110
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