About: Changes in hemocoagulation in acute stroke patients after one-hour sono-thrombolysis using a diagnostic probe.

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About: Changes in hemocoagulation in acute stroke patients after one-hour sono-thrombolysis using a diagnostic probe. Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The aim was to monitor the changes in hemocoagulation parameters in acute ischemic stroke (AIS) patients after sono-thrombolysis of the occluded middle cerebral artery using a duplex transcranial probe with 2.0-MHz frequency in Doppler mode. Sixteen AIS patients indicated for intravenous thrombolysis (IVT) (8 males; mean age 68.3 +/- 7.1 y) and 16 AIS patients contraindicated for IVT (11 males; mean age 67.9 +/- 7.9 y) were randomized for sono-thrombolysis (8 + 8 patients) or standard treatment (control group) (8 + 8 patients). The significant decrease of plasminogen activator inhibitor-1, plasminogen and alpha-2-antiplasmin activity by a mean of 60, 32 and 24%, respectively, and the increase of tissue plasminogen activator by a mean of 56% was found after sono-thrombolysis when compared with control group (p { 0.0125); these changes were more evident in patients treated with a combination of sono-thrombolysis and IVT (79, 38, 50 and 82%, respectively) than in patients treated by sono-thrombolysis alone (34, 13, 17 and 30%, respectively). The aim was to monitor the changes in hemocoagulation parameters in acute ischemic stroke (AIS) patients after sono-thrombolysis of the occluded middle cerebral artery using a duplex transcranial probe with 2.0-MHz frequency in Doppler mode. Sixteen AIS patients indicated for intravenous thrombolysis (IVT) (8 males; mean age 68.3 +/- 7.1 y) and 16 AIS patients contraindicated for IVT (11 males; mean age 67.9 +/- 7.9 y) were randomized for sono-thrombolysis (8 + 8 patients) or standard treatment (control group) (8 + 8 patients). The significant decrease of plasminogen activator inhibitor-1, plasminogen and alpha-2-antiplasmin activity by a mean of 60, 32 and 24%, respectively, and the increase of tissue plasminogen activator by a mean of 56% was found after sono-thrombolysis when compared with control group (p { 0.0125); these changes were more evident in patients treated with a combination of sono-thrombolysis and IVT (79, 38, 50 and 82%, respectively) than in patients treated by sono-thrombolysis alone (34, 13, 17 and 30%, respectively). (en)
Title	Changes in hemocoagulation in acute stroke patients after one-hour sono-thrombolysis using a diagnostic probe. Changes in hemocoagulation in acute stroke patients after one-hour sono-thrombolysis using a diagnostic probe. (en)
skos:prefLabel	Changes in hemocoagulation in acute stroke patients after one-hour sono-thrombolysis using a diagnostic probe. Changes in hemocoagulation in acute stroke patients after one-hour sono-thrombolysis using a diagnostic probe. (en)
skos:notation	RIV/61989592:15110/10:33117968!RIV13-MZ0-15110___
http://linked.open...avai/riv/aktivita	P V
http://linked.open...avai/riv/aktivity	P(NR9487), V
http://linked.open...iv/cisloPeriodika	7
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Langová, Kateřina Šaňák, Daniel KAŇOVSKÝ, Petr Herzig, Roman Školoudík, David
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Lékařská fakulta
http://linked.open...dnocenehoVysledku	250294
http://linked.open...ai/riv/idVysledku	RIV/61989592:15110/10:33117968
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	sono-thrombolysis; acute stroke; hemocoagulation (en)
http://linked.open.../riv/klicoveSlovo	acute stroke hemocoagulation sono-thrombolysis
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[70AF2ADDE11A]
http://linked.open...i/riv/nazevZdroje	Ultrasound in Medicine and Biology
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	11 (xsd:int)
http://linked.open...vavai/riv/projekt	Activation of fybrinolytic system using continual sonography monitoring in acute stroke patients and in volunteers
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	36
http://linked.open...iv/tvurceVysledku	Blatný, J. Langová, Kateřina Šaňák, Daniel Školoudík, David Fadrná, Táňa Herzig, Roman Kaňovský, Petr Roubec, Martin Bar, Michal Zapletal, Ondřej Bardoň, Petr
http://linked.open...ain/vavai/riv/wos	000279066000002
issn	0301-5629
number of pages	8 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.ultrasmedbio.2010.04.010
http://localhost/t...ganizacniJednotka	15110

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