About: LAPATINIB IN BREAST CANCER ? THE PREDICTIVE SIGNIFICANCE OF HER1 (EGFR), HER2, PTEN AND PIK3CA GENES AND LAPATINIB PLASMA LEVEL ASSESSMENT.     Goto   Sponge   NotDistinct   Permalink

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Description
  • Breast cancer treatment trends are currently based on tailored therapies using tumor and patient biomarkers. Lapatinib is the first dual inhibitor of HER1 (EGFR, ErbB1)and HER2 (ErbB2, Neu) tyrosine kinases to be used in clinical practice. However, only HER2 is currently used for therapy indications and new predictors for the treatment with lapatinib are sought.
  • Breast cancer treatment trends are currently based on tailored therapies using tumor and patient biomarkers. Lapatinib is the first dual inhibitor of HER1 (EGFR, ErbB1)and HER2 (ErbB2, Neu) tyrosine kinases to be used in clinical practice. However, only HER2 is currently used for therapy indications and new predictors for the treatment with lapatinib are sought. (en)
Title
  • LAPATINIB IN BREAST CANCER ? THE PREDICTIVE SIGNIFICANCE OF HER1 (EGFR), HER2, PTEN AND PIK3CA GENES AND LAPATINIB PLASMA LEVEL ASSESSMENT.
  • LAPATINIB IN BREAST CANCER ? THE PREDICTIVE SIGNIFICANCE OF HER1 (EGFR), HER2, PTEN AND PIK3CA GENES AND LAPATINIB PLASMA LEVEL ASSESSMENT. (en)
skos:prefLabel
  • LAPATINIB IN BREAST CANCER ? THE PREDICTIVE SIGNIFICANCE OF HER1 (EGFR), HER2, PTEN AND PIK3CA GENES AND LAPATINIB PLASMA LEVEL ASSESSMENT.
  • LAPATINIB IN BREAST CANCER ? THE PREDICTIVE SIGNIFICANCE OF HER1 (EGFR), HER2, PTEN AND PIK3CA GENES AND LAPATINIB PLASMA LEVEL ASSESSMENT. (en)
skos:notation
  • RIV/61989592:15110/10:10214978!RIV11-MZ0-15110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(NS10286), S, Z(MSM6198959216)
http://linked.open...iv/cisloPeriodika
  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 267891
http://linked.open...ai/riv/idVysledku
  • RIV/61989592:15110/10:10214978
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Lapatinib plasma level; Metastatic breast cancer; Biological therapy; Targeted therapy; Dual tyrosine kinase inhibitor; PIK3CA; PTEN; HER2 (ErbB2, Neu); HER1 (EGFR, ErbB1); Lapatinib (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [35635D93CA57]
http://linked.open...i/riv/nazevZdroje
  • Biomedical Papers
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 154
http://linked.open...iv/tvurceVysledku
  • BOUCHALOVÁ, Kateřina
  • Hajdúch, Marián
  • ČÍŽKOVÁ, Magdalena
  • CWIERTKA, Karel
  • FRIEDECKÝ, David
  • TROJANEC, Radek
http://linked.open...n/vavai/riv/zamer
issn
  • 1213-8118
number of pages
http://localhost/t...ganizacniJednotka
  • 15110
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