About: Characterization of Pseudacyclins A-E, a Suite of Cyclic Peptides Produced Pseudallescheria boydii

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About: Characterization of Pseudacyclins A-E, a Suite of Cyclic Peptides Produced Pseudallescheria boydii Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Pseudallescheria boydii sensu lato is an emerging fungal pathogen causing fatal infections in both immunocompromised and immunocompetent hosts. In this work, two P. boydii isolates (human and animal origin) have been identified as being producers of cyclic peptides. Five putative nonribosomal peptides with a unique structure, which have been named pseudacyclins, were characterized by nuclear magnetic resonance spectroscopy and mass spectrometry. The most abundant representative of the pseudacyclins was quantified also on fungal spores. The presence of these peptides on inhaled fungal spores creates the possibility for exploitation of pseudacyclins as early indicators of fungal infections caused by Pseudallescheria species. Pseudallescheria boydii sensu lato is an emerging fungal pathogen causing fatal infections in both immunocompromised and immunocompetent hosts. In this work, two P. boydii isolates (human and animal origin) have been identified as being producers of cyclic peptides. Five putative nonribosomal peptides with a unique structure, which have been named pseudacyclins, were characterized by nuclear magnetic resonance spectroscopy and mass spectrometry. The most abundant representative of the pseudacyclins was quantified also on fungal spores. The presence of these peptides on inhaled fungal spores creates the possibility for exploitation of pseudacyclins as early indicators of fungal infections caused by Pseudallescheria species. (en)
Title	Characterization of Pseudacyclins A-E, a Suite of Cyclic Peptides Produced Pseudallescheria boydii Characterization of Pseudacyclins A-E, a Suite of Cyclic Peptides Produced Pseudallescheria boydii (en)
skos:prefLabel	Characterization of Pseudacyclins A-E, a Suite of Cyclic Peptides Produced Pseudallescheria boydii Characterization of Pseudacyclins A-E, a Suite of Cyclic Peptides Produced Pseudallescheria boydii (en)
skos:notation	RIV/61989592:15110/10:10213291!RIV11-MSM-15110___
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(LC07017), S, Z(MSM6198959216)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Hajdúch, Marián
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Lékařská fakulta
http://linked.open...dnocenehoVysledku	250439
http://linked.open...ai/riv/idVysledku	RIV/61989592:15110/10:10213291
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Pseudallescheria boydii sensu lato (en)
http://linked.open.../riv/klicoveSlovo	Pseudallescheria boydii sensu lato
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[7CE60B47C00A]
http://linked.open...i/riv/nazevZdroje	Journal of Natural Products
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	14 (xsd:int)
http://linked.open...vavai/riv/projekt	Oncoproteomics Centre
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	73
http://linked.open...iv/tvurceVysledku	Benada, Oldřich Hajdúch, Marián Kuzma, Marek Lemr, Karel Novák, Petr Pavlásková, Kateřina Sklenář, Jan Šulc, Miroslav Žabka, Martin Havlíček, Vladimír Nedvěd, Jan Kofroňová, Olga Derrick, Peter J. Jegorov, Alexander
http://linked.open...n/vavai/riv/zamer	Modulation of signalling and regulatory pathways in normal and cancer cells
issn	0163-3864
number of pages	6 (xsd:int)
http://localhost/t...ganizacniJednotka	15110

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