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  • CORS-26 (collagenous repeat- containing sequence of 26 kDa protein) is a newly discovered adipokine of the C1q/TNF molecular superfamily C1q/TNF-related protein-3 (CTRP-3) secreted, inter alia in murine monocytes and adipocytes and in human adipocytes. CORS-26 is much less known than other adipocytes such as leptin and resistin. This review aims to provide current knowledge of this adipokine. Review; sources were scientific biomedical databases Medline/PubMed, BioMedCentral, Google Scholar, Ovid, ProQuest from to 1998 to 2009. CORS-26 is an adipokine that regulates the secretion of other adipokines. Its effects on adipokine secretion are most probably independent of PPAR-gama. As CORS-26 up-regulates adiponectin secretion, it may be involved in metabolic and immunologic pathways. The effect of recombinant CORS-26 on insulin signaling in the presence of the metabolic syndrome needs to be investigated to further evaluate the physiological and pathophysiological role of this protein.
  • CORS-26 (collagenous repeat- containing sequence of 26 kDa protein) is a newly discovered adipokine of the C1q/TNF molecular superfamily C1q/TNF-related protein-3 (CTRP-3) secreted, inter alia in murine monocytes and adipocytes and in human adipocytes. CORS-26 is much less known than other adipocytes such as leptin and resistin. This review aims to provide current knowledge of this adipokine. Review; sources were scientific biomedical databases Medline/PubMed, BioMedCentral, Google Scholar, Ovid, ProQuest from to 1998 to 2009. CORS-26 is an adipokine that regulates the secretion of other adipokines. Its effects on adipokine secretion are most probably independent of PPAR-gama. As CORS-26 up-regulates adiponectin secretion, it may be involved in metabolic and immunologic pathways. The effect of recombinant CORS-26 on insulin signaling in the presence of the metabolic syndrome needs to be investigated to further evaluate the physiological and pathophysiological role of this protein. (en)
Title
  • COLLAGENOUS REPEAT-CONTAINING SEQUENCE OF 26 kDa PROTEIN
  • COLLAGENOUS REPEAT-CONTAINING SEQUENCE OF 26 kDa PROTEIN (en)
skos:prefLabel
  • COLLAGENOUS REPEAT-CONTAINING SEQUENCE OF 26 kDa PROTEIN
  • COLLAGENOUS REPEAT-CONTAINING SEQUENCE OF 26 kDa PROTEIN (en)
skos:notation
  • RIV/61989592:15110/10:10212713!RIV11-MSM-15110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM6198959216)
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 251152
http://linked.open...ai/riv/idVysledku
  • RIV/61989592:15110/10:10212713
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Chondrogenesis; Osteosarcoma; Metabolic syndrome; Adipose tissue; Adipokines; Cartducin; CORS-2 (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [4FDF30A77240]
http://linked.open...i/riv/nazevZdroje
  • Biomedical Papers
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 154
http://linked.open...iv/tvurceVysledku
  • Stejskal, David
  • Sporová, Lenka
  • Švesták, Marek
  • Hejduk, Marek
  • Lacnak, Bořek
http://linked.open...n/vavai/riv/zamer
issn
  • 1213-8118
number of pages
http://localhost/t...ganizacniJednotka
  • 15110
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