About: The phytogenic feed additive Sangrovit modulates dextran sulfate sodium-induced colitis in rats

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About: The phytogenic feed additive Sangrovit modulates dextran sulfate sodium-induced colitis in rats Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Macleaya cordata is an active component of the feed addi?tive Sangrovit. The study was conducted to evaluate the effects of Sangrovit on dextran sulfate sodium (DSS) induced colitis in rats. Rats were assigned to three groups. Group 1 received standard diet and tap water for 14 days, group 2 received 500 ppm Sangrovit in their feed for 14 days and in the second week 5% DSS in the tap water. Group 3 was fed with standard diet, in the second week with 5% DSS in the tap water. The following parameters were measured: organ weight, myeloperoxidase activity, expression of cyclooxy?genase-2, hematological parameters, histological analysis and parameters of oxidative stress. The animals from Groups 2 and 3 showed increases in organ weight and changes in the hematological parameters. DSS caused diffuse injury, the Sangrovit group showed less severe damage to the colon mucosa. The Sangrovit diminished expression of DSS induced cyclooxy?genase-2 and mitigated myeloperoxidase activity in colon. Macleaya cordata is an active component of the feed addi?tive Sangrovit. The study was conducted to evaluate the effects of Sangrovit on dextran sulfate sodium (DSS) induced colitis in rats. Rats were assigned to three groups. Group 1 received standard diet and tap water for 14 days, group 2 received 500 ppm Sangrovit in their feed for 14 days and in the second week 5% DSS in the tap water. Group 3 was fed with standard diet, in the second week with 5% DSS in the tap water. The following parameters were measured: organ weight, myeloperoxidase activity, expression of cyclooxy?genase-2, hematological parameters, histological analysis and parameters of oxidative stress. The animals from Groups 2 and 3 showed increases in organ weight and changes in the hematological parameters. DSS caused diffuse injury, the Sangrovit group showed less severe damage to the colon mucosa. The Sangrovit diminished expression of DSS induced cyclooxy?genase-2 and mitigated myeloperoxidase activity in colon. (en)
Title	The phytogenic feed additive Sangrovit modulates dextran sulfate sodium-induced colitis in rats The phytogenic feed additive Sangrovit modulates dextran sulfate sodium-induced colitis in rats (en)
skos:prefLabel	The phytogenic feed additive Sangrovit modulates dextran sulfate sodium-induced colitis in rats The phytogenic feed additive Sangrovit modulates dextran sulfate sodium-induced colitis in rats (en)
skos:notation	RIV/61989592:15110/10:10212290!RIV11-GA0-15110___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA525/07/0871), P(GD303/09/H048), Z(MSM6198959216)
http://linked.open...iv/cisloPeriodika	12
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	EHRMANN, Jiří Šimánek, Vilím Palíková, Irena VEČEŘA, Rostislav Vacek, Jan Ulrichová, Jitka Vostálová, Jitka Cibiček, Norbert Vrublová, Eva
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Lékařská fakulta
http://linked.open...dnocenehoVysledku	278949
http://linked.open...ai/riv/idVysledku	RIV/61989592:15110/10:10212290
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	myeloperoxidase; cyclooxygenase-2; dextran sulfate sodium-induced colitis; feed additive; protopines; benzo[c]phenanthridines; Papaveraceae; Macleaya cordata (en)
http://linked.open.../riv/klicoveSlovo	Macleaya cordata myeloperoxidase cyclooxygenase-2 Papaveraceae protopines benzo[c]phenanthridines dextran sulfate sodium-induced colitis feed additive
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[B0447BDA466E]
http://linked.open...i/riv/nazevZdroje	Veterinární medicína
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	9 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	Molecular mechanisms of selected pathological processes in the cell Detoxification of quaternary isoquinoline alkaloids in vitro and in vivo, biological activity of their metabolites
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	55
http://linked.open...iv/tvurceVysledku	EHRMANN, Jiří Ulrichová, Jitka Vostálová, Jitka Vacek, Jan VEČEŘA, Rostislav Šimánek, Vilím Vrublová, Eva VRBKOVÁ, Jana CIBIČEK, Norbert ŠVARCOVÁ, Irena
http://linked.open...n/vavai/riv/zamer	Modulation of signalling and regulatory pathways in normal and cancer cells
issn	0375-8427
number of pages	9 (xsd:int)
http://localhost/t...ganizacniJednotka	15110

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