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rdf:type
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Description
| - The prognostic and predictive value of the epidermal growth factor receptor (EGFR) expression and some genetic alternations in the EGFR signal pathway, such as EGFR amplification, EGFR-activationg tyroskine kinase mutations or the k-ras gene mutation, were investigated in our study. The aim of the research to evaluate the occurence of the above-mentioned biomarkers in correlation with the therapeutic response and survival in patients with spinocellular head and neck cancers. The presence of activating mutationts in the EGFR tyroskine domain, the k-ras mutation, and the correlation between EGFR gene amplification and receptor expression were proved.
- The prognostic and predictive value of the epidermal growth factor receptor (EGFR) expression and some genetic alternations in the EGFR signal pathway, such as EGFR amplification, EGFR-activationg tyroskine kinase mutations or the k-ras gene mutation, were investigated in our study. The aim of the research to evaluate the occurence of the above-mentioned biomarkers in correlation with the therapeutic response and survival in patients with spinocellular head and neck cancers. The presence of activating mutationts in the EGFR tyroskine domain, the k-ras mutation, and the correlation between EGFR gene amplification and receptor expression were proved. (en)
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Title
| - Mutations in EGFR signal pathway in correlation with response to treatment of head and neck cancers
- Mutations in EGFR signal pathway in correlation with response to treatment of head and neck cancers (en)
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skos:prefLabel
| - Mutations in EGFR signal pathway in correlation with response to treatment of head and neck cancers
- Mutations in EGFR signal pathway in correlation with response to treatment of head and neck cancers (en)
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skos:notation
| - RIV/61989592:15110/09:00009548!RIV10-MSM-15110___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(LC07017), P(NR9200), P(NS10108), S, V, Z(MSM6198959216)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15110/09:00009548
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - head and neck cancer; EGFr; predictive markers (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Scripta Medica Facultatis Medicae Universitatis Brunensis Masarykianae
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Hajdúch, Marián
- Berkovcová, Jitka
- Kostřica, R.
- Neuwirthová, J.
- Rottenberg, J.
- Smilek, P.
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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