About: Growth Strategy of the Pathogenic Yeast Cryptococcus neoformans Submerged Culture under Different Cultivation Formats

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Growth patterns of Cryptococcus neoformans submerged culture in different culture volumes, intensity of agitation and types of sealing were evaluated to better understand the physiological role of hypoxia response in this yeast. When low intensity agitation was set at high culture volumes and air exchange between the cultivation vessel and external environment was not abolished completely, the cells proliferated slowly but steadily. On the other hand, when the intensity of agitation was high but the vessel was withheld from fresh air supply, the cells first proliferated rapidly, then arrested completely and finally died. Therefore, the central strategy of C. neoformans here seems to lie in its proliferation-rate adjustment to the available oxygen levels and not in its capacity to survive under anoxia. The data support the opinion that the cultures grown under limited aeration (even though not completely withheld from fresh air supply) are much closer to the real cryptococcal life in human tissues than Growth patterns of Cryptococcus neoformans submerged culture in different culture volumes, intensity of agitation and types of sealing were evaluated to better understand the physiological role of hypoxia response in this yeast. When low intensity agitation was set at high culture volumes and air exchange between the cultivation vessel and external environment was not abolished completely, the cells proliferated slowly but steadily. On the other hand, when the intensity of agitation was high but the vessel was withheld from fresh air supply, the cells first proliferated rapidly, then arrested completely and finally died. Therefore, the central strategy of C. neoformans here seems to lie in its proliferation-rate adjustment to the available oxygen levels and not in its capacity to survive under anoxia. The data support the opinion that the cultures grown under limited aeration (even though not completely withheld from fresh air supply) are much closer to the real cryptococcal life in human tissues than (en)
Title	Growth Strategy of the Pathogenic Yeast Cryptococcus neoformans Submerged Culture under Different Cultivation Formats Growth Strategy of the Pathogenic Yeast Cryptococcus neoformans Submerged Culture under Different Cultivation Formats (en)
skos:prefLabel	Growth Strategy of the Pathogenic Yeast Cryptococcus neoformans Submerged Culture under Different Cultivation Formats Growth Strategy of the Pathogenic Yeast Cryptococcus neoformans Submerged Culture under Different Cultivation Formats (en)
skos:notation	RIV/61989592:15110/09:00009529!RIV10-MSM-15110___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA310/06/0645), Z(MSM6198959223)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Husičková, Vendula Raclavský, Vladislav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Lékařská fakulta
http://linked.open...dnocenehoVysledku	316748
http://linked.open...ai/riv/idVysledku	RIV/61989592:15110/09:00009529
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Cryptococcus neoformans; Hypoxia; Pathogenesis (en)
http://linked.open.../riv/klicoveSlovo	Cryptococcus neoformans Pathogenesis Hypoxia
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[C1F5EB431DFD]
http://linked.open...i/riv/nazevZdroje	Folia Microbiologica
http://linked.open...in/vavai/riv/obor	EE
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Hypoxia response in the pathogenic yeast Cryptococcus neoformans
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	54
http://linked.open...iv/tvurceVysledku	Husičková, Vendula Raclavský, Vladislav Trtková, Jitka Přeček, J. Moráňová, Zuzana Fischer, O. Kawamoto, S. Ohkusu, M. Takeo, K.
http://linked.open...n/vavai/riv/zamer	Nové možnosti diagnostiky a imunomodulace u infekčních onemocnění a imunopatologických stavů
issn	0015-5632
number of pages	4 (xsd:int)
http://localhost/t...ganizacniJednotka	15110

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