About: Circulating Vascular Endothelial Growth Factor, C.reactive Protein and Urinary Neopterin Concentrations During dose-dense Chemotherapy     Goto   Sponge   NotDistinct   Permalink

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  • Sledovány změny neopterinu a VEGF během chemoterapie (cs)
  • Angiogenesis plays a crucial role in tumor progression. Prominent among angiogenic factors is vascular endothelial growth factor (VEGF). VEGF is produced by cancer cells as well as by the cells infiltrating tumor stroma, mainly macrophages. Macrophage activation may be assessed by measuring serum or urinary neopterin. Systemic inflammatory response could be evaluated by measuring serum C-reactive protein concentrations. The aim of the present study was to examine the effect of a regimen combining dose dense combination of doxorubicin and cyclophosphamide with sequential weekly paclitaxel on plasma VEGF, urinary neopterin and serum C-reactive protein concentrations. Thirty-four female patients with histologically verified breast carcinoma treated with dose-dense regimen combining doxorubicin and cyclophosphamide with sequential weekly paclitaxel administration were studied. Plasma VEGF was measured by enzyme-linked immunosorbent assay. Urinary neopterin was determined by high performance liquid chromat
  • Angiogenesis plays a crucial role in tumor progression. Prominent among angiogenic factors is vascular endothelial growth factor (VEGF). VEGF is produced by cancer cells as well as by the cells infiltrating tumor stroma, mainly macrophages. Macrophage activation may be assessed by measuring serum or urinary neopterin. Systemic inflammatory response could be evaluated by measuring serum C-reactive protein concentrations. The aim of the present study was to examine the effect of a regimen combining dose dense combination of doxorubicin and cyclophosphamide with sequential weekly paclitaxel on plasma VEGF, urinary neopterin and serum C-reactive protein concentrations. Thirty-four female patients with histologically verified breast carcinoma treated with dose-dense regimen combining doxorubicin and cyclophosphamide with sequential weekly paclitaxel administration were studied. Plasma VEGF was measured by enzyme-linked immunosorbent assay. Urinary neopterin was determined by high performance liquid chromat (en)
Title
  • Circulating Vascular Endothelial Growth Factor, C.reactive Protein and Urinary Neopterin Concentrations During dose-dense Chemotherapy
  • Sledovány změny neopterinu a VEGF během chemoterapie (cs)
  • Circulating Vascular Endothelial Growth Factor, C.reactive Protein and Urinary Neopterin Concentrations During dose-dense Chemotherapy (en)
skos:prefLabel
  • Circulating Vascular Endothelial Growth Factor, C.reactive Protein and Urinary Neopterin Concentrations During dose-dense Chemotherapy
  • Sledovány změny neopterinu a VEGF během chemoterapie (cs)
  • Circulating Vascular Endothelial Growth Factor, C.reactive Protein and Urinary Neopterin Concentrations During dose-dense Chemotherapy (en)
skos:notation
  • RIV/61989592:15110/08:00007567!RIV09-MSM-15110___
http://linked.open...avai/riv/aktivita
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  • 360011
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  • RIV/61989592:15110/08:00007567
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  • breast carcinoma; C-reactive protein; cyclophosphamide; doxorubicin; neopterin; paclitaxel; vascular endothelial growth factor (en)
http://linked.open.../riv/klicoveSlovo
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  • GB - Spojené království Velké Británie a Severního Irska
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  • [1EA471F567EC]
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http://linked.open...v/svazekPeriodika
  • 19
http://linked.open...iv/tvurceVysledku
  • Hornychová, Helena
  • Hyšpler, Radomír
  • Krčmová, Lenka
  • Melichar, Bohuslav
  • Ryška, Aleš
  • Solichová, Dagmar
  • Urbánek, Lubor
  • Balloková, Anna
  • Malírová, Eva
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  • 0933-4807
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  • 15110
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