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Description
  • Změny v expresi buněčných receptorů přispívají k růstu mnoha závažných typů tumorů. V tomto review se zaměříme na normální roli Erb B receptorů jako signálu transducerů a jejich příspěvek ke karcinogenezi, kdy se jedná o abnormality v Erb B signalizaci z důvodu přemíry aktivity receptorů nebo přemíry exprese ligandů, které mohou vést k rozvoji defektů a bývají spojovány s mnoha typy rakoviny. (cs)
  • Changes in the expression of cellular receptors contribute to the progression of many types of solid tumors. In this review, we focus on the normal role of ErbB receptors as signal transducers and their contribution to carcinogenesis when there are abnormalities in ErbB signaling due to the overactivity of the receptors or the overexpression of ligands, which can lead to developmental defects and have been associated with many types of cancers.
  • Changes in the expression of cellular receptors contribute to the progression of many types of solid tumors. In this review, we focus on the normal role of ErbB receptors as signal transducers and their contribution to carcinogenesis when there are abnormalities in ErbB signaling due to the overactivity of the receptors or the overexpression of ligands, which can lead to developmental defects and have been associated with many types of cancers. (en)
Title
  • The status and role of ErbB receptors in human cancer.
  • The status and role of ErbB receptors in human cancer. (en)
  • Význam a role ErbB receptorů u rakoviny člověka. (cs)
skos:prefLabel
  • The status and role of ErbB receptors in human cancer.
  • The status and role of ErbB receptors in human cancer. (en)
  • Význam a role ErbB receptorů u rakoviny člověka. (cs)
skos:notation
  • RIV/61989592:15110/08:00005861!RIV09-MPO-15110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(1H-PK/45), P(LC07017), S, Z(MSM6198959216)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 397348
http://linked.open...ai/riv/idVysledku
  • RIV/61989592:15110/08:00005861
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • ErbB receptor (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [8EA4E654532F]
http://linked.open...i/riv/nazevZdroje
  • Experimental and molecular pathology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 84
http://linked.open...iv/tvurceVysledku
  • Hajdúch, Marián
  • Überall, Ivo
  • Kolář, Zdeněk
  • Berkovcová, Jitka
  • Trojanec, Radek
http://linked.open...n/vavai/riv/zamer
issn
  • 0014-4800
number of pages
http://localhost/t...ganizacniJednotka
  • 15110
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