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  • Objective: To describe histological and ultrastructural changes of cardiomyocytes in experimental rats following subplantar administration of carrageenin. Material and Methods: In adult rats, an acute inflammatory reaction was induced by subplantar injection of 0.1 ml of 1% sterile carrageenin solution. In a total of 10 rats, which developed gangrene of tails in 5- to 12-cm-long segments, were killed and their internal organs fixed in 10% formaldehyde solution and subsequently processed for paraffin embedding.Normal cardiomyocytes were observed in control rats. Complicating thrombosis of tail blood vessels leading to extensive tail necroses were also histologically confirmed. Conclusion: These findings demonstrate specific pathogenic effect in the cardiovascular system of the carrageenin-treated rats.
  • Objective: To describe histological and ultrastructural changes of cardiomyocytes in experimental rats following subplantar administration of carrageenin. Material and Methods: In adult rats, an acute inflammatory reaction was induced by subplantar injection of 0.1 ml of 1% sterile carrageenin solution. In a total of 10 rats, which developed gangrene of tails in 5- to 12-cm-long segments, were killed and their internal organs fixed in 10% formaldehyde solution and subsequently processed for paraffin embedding.Normal cardiomyocytes were observed in control rats. Complicating thrombosis of tail blood vessels leading to extensive tail necroses were also histologically confirmed. Conclusion: These findings demonstrate specific pathogenic effect in the cardiovascular system of the carrageenin-treated rats. (en)
Title
  • Histological and Ultrastructural Changes of Cardiomyocytes in Experimental Rats with Tail Thrombosis following Subplantar Application of Carrageenin
  • Histological and Ultrastructural Changes of Cardiomyocytes in Experimental Rats with Tail Thrombosis following Subplantar Application of Carrageenin (en)
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  • Histological and Ultrastructural Changes of Cardiomyocytes in Experimental Rats with Tail Thrombosis following Subplantar Application of Carrageenin
  • Histological and Ultrastructural Changes of Cardiomyocytes in Experimental Rats with Tail Thrombosis following Subplantar Application of Carrageenin (en)
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  • RIV/61989592:15110/07:10224732!RIV12-MSM-15110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I
http://linked.open...iv/cisloPeriodika
  • 5
http://linked.open...vai/riv/dodaniDat
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  • 424191
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  • RIV/61989592:15110/07:10224732
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  • granular deposits; mitochondrial cardiomyopathy; rat tail thrombosis; Carrageenin (en)
http://linked.open.../riv/klicoveSlovo
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  • CH - Švýcarská konfederace
http://linked.open...ontrolniKodProRIV
  • [8C8A691F0750]
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  • Medical Principles and Practice
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http://linked.open...v/svazekPeriodika
  • 16
http://linked.open...iv/tvurceVysledku
  • Krajčí, Dimitrolos
  • Jezdinský, Jaroslav
  • Koďousek, Rostislav
issn
  • 1011-7571
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http://localhost/t...ganizacniJednotka
  • 15110
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