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| Description
| - Cílem studie bylo pomocí klinického sledování zhodnotit spolehlivost biopsie sentinelových lymfatických uzlin (SLU) při detekci uzlinových metastáz u pacientů (pac.) s maligním melanomem (MM). Celkem byla SLU biopsie provedena u 170 pac. s MM. 2 pacienti s lokální recidivou MM byli vyloučeni ze studie pro možnost vzniku uzlinové metastázy na základě recidivy. Celkem hodnoceno 168 osob. Lokalizace MM: 91 trup, 67 končetiny, 10 hlava a krk. TNM: 48 pT1, 65 pT2, 32 pT3, 19 pT4, 4 pTiS. Střední doba sledování 2,6 roku (0,5-5,7, medián 2,4 roku). SLU nalezeny u všech pac. ? 100% úspěšnost detekce SLU. Metastázy v SLU detekovány u 25/168 pac. (1/48 pT1, 6/65 pT2, 8/32 pT3, 10/19 pT4). Následné klinické sledování zjistilo lymfatické metastázy u dalších 4 pac.(1 pT2, 1pT3, 2 pT4), z toho ve 3 případech šlo o MM na distálních partiích dolních končetin. Senzitivita SLU biopsie 86 %, negativní prediktivní hodnota 97 %. Při hodnocení bez 6 pacientů s MM na noze: senzitivita 96,1%, NPV 99,3%. U 3 pac. zjištěny vz (cs)
- Introduction: Sentinellymph node (SLN) biopsy and subsequent clinical assessment show different results in some patients with malignant melanoma (MM). The incidence of a false negative SLN is less than 2% in a case of comparison of SLN status with a histological finding in the remaining lymph nodes in the Iymphatic basin. However, the incidence of lymphatic metastases in the adjacent lymphatic basins varies in patients with negative SLN from4% to 27% duringthe follow-up (Mariani G et a1.JNucl Med 2002; 43: 811-827). The aim of the study was to evaluate this parameter in a large group ofpatients. Methods: 170 consecutive patients with MM underwent SLN biopsy and subsequently were followed at the Dept. of Oncology. 2 patients were excluded from the study due to the local recurrence with secondary lymph node metastasis, therefore a total of 168 patients were studied. Loca1ization of MMs: 91 trunk, 67 extremities, 10 head and neck. TNM classification: 48 pTI, 65 pT2, 32 pT3, 19 pT4, 4 pTiS. T
- Introduction: Sentinellymph node (SLN) biopsy and subsequent clinical assessment show different results in some patients with malignant melanoma (MM). The incidence of a false negative SLN is less than 2% in a case of comparison of SLN status with a histological finding in the remaining lymph nodes in the Iymphatic basin. However, the incidence of lymphatic metastases in the adjacent lymphatic basins varies in patients with negative SLN from4% to 27% duringthe follow-up (Mariani G et a1.JNucl Med 2002; 43: 811-827). The aim of the study was to evaluate this parameter in a large group ofpatients. Methods: 170 consecutive patients with MM underwent SLN biopsy and subsequently were followed at the Dept. of Oncology. 2 patients were excluded from the study due to the local recurrence with secondary lymph node metastasis, therefore a total of 168 patients were studied. Loca1ization of MMs: 91 trunk, 67 extremities, 10 head and neck. TNM classification: 48 pTI, 65 pT2, 32 pT3, 19 pT4, 4 pTiS. T (en)
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| Title
| - Efficacy of sentinel lymph node biopsy in patients with malignant melanoma
- Spolehlivost biopsie sentinelových uzlin u maligního melanomu (cs)
- Efficacy of sentinel lymph node biopsy in patients with malignant melanoma (en)
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| skos:prefLabel
| - Efficacy of sentinel lymph node biopsy in patients with malignant melanoma
- Spolehlivost biopsie sentinelových uzlin u maligního melanomu (cs)
- Efficacy of sentinel lymph node biopsy in patients with malignant melanoma (en)
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| skos:notation
| - RIV/61989592:15110/07:00004356!RIV08-MSM-15110___
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/61989592:15110/07:00004356
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - sentinel lymph node biopsy; malignant melanoma (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - DE - Spolková republika Německo
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Beneš, Petr
- Koranda, Pavel
- Kamínek, Milan
- Mysliveček, Miroslav
- Bajgar, Robert
- Molitor, M.
- Hirňák, J.
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| number of pages
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| http://localhost/t...ganizacniJednotka
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